2-(2-Hydroxy-1-oxopropoxy)propionic acid

Base Information

• Chemical Name: 2-(2-Hydroxy-1-oxopropoxy)propionic acid
• CAS No.: 617-57-2
• Molecular Formula: C6H10O5
• Molecular Weight: 162.142
• European Community (EC) Number: 210-520-1
• UNII: N37QW3EK1L
• DSSTox Substance ID: DTXSID30862299
• Nikkaji Number: J4.949B
• Wikidata: Q27284504
• Mol file: 617-57-2.mol

Synonyms:lactyl lactate

Chemical Property of 2-(2-Hydroxy-1-oxopropoxy)propionic acid

Chemical Property:

• Vapor Pressure: 0.00329mmHg at 25°C
• Refractive Index: 1.47
• Boiling Point: 315.2 °C at 760 mmHg
• Flash Point: 132.4 °C
• PSA: 83.83000
• Density: 1.308 g/cm³
• LogP: -0.61650
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 162.05282342
• Heavy Atom Count: 11
• Complexity: 164

Purity/Quality:

99%, ^*data from raw suppliers

2-LACTOYLOXYPROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)OC(C)C(=O)O)O

Technology Process of 2-(2-Hydroxy-1-oxopropoxy)propionic acid

There total 11 articles about 2-(2-Hydroxy-1-oxopropoxy)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

LACTIC ACID (849585-22-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6) → 2-(2-hydroxy-1-oxopropoxy)propionic acid (617-57-2) + D,L-lactide (95-96-5,26680-10-4,26969-66-4,615-95-2)

Guidance literature:

at 150 ℃; inactive-lactide; im Luftstrom;

Reference yield:

LACTIC ACID (849585-22-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6) + calcium lactate (814-80-2) → 2-(2-hydroxy-1-oxopropoxy)propionic acid (617-57-2) + D,L-lactide (95-96-5,26680-10-4,26969-66-4,615-95-2)

Guidance literature:

LACTIC ACID; calcium lactate; at 110 ℃; for 1.5h; under 760.051 Torr;

With phosphoric acid; In water;

Reference yield:

magnesium methylglycolate → LACTIC ACID (849585-22-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6) + 2-(2-hydroxy-1-oxopropoxy)propionic acid (617-57-2) + D,L-lactide (95-96-5,26680-10-4,26969-66-4,615-95-2)

Guidance literature:

With calcium dihydrogen phosphate; phosphoric acid; In water; at 80 - 180 ℃; under 3.0003 - 760.051 Torr;

upstream raw materials:

LACTIC ACID

water

2-Bromopropionic acid

calcium lactate

Downstream raw materials:

isopropyl lactate

N-methyl-N-phenyl-α-hydroxypropanamide

(+/-)-lactamide

acetaldehyde

Refernces

• 1、 Liu, Lijuan,Xu, Xiaolong. "A study on highly concentrated lactic acid and the synthesis of lactide from its solution". . p. 856 - 864. Retrieved 2021/06/16.
• 2、 -. "PROCESS FOR THE MANUFACTURE OF LACTIDE". Page/Page column 9-10. . Retrieved 2012/01/14.