2-NITROANILINE-4-SULFONIC ACID SODIUM SALT

Base Information

• Chemical Name: 2-NITROANILINE-4-SULFONIC ACID SODIUM SALT
• CAS No.: 5042-33-1
• Molecular Formula: C6H5N2NaO5S
• Molecular Weight: 240.172
• Hs Code.: 2921420090
• Mol file: 5042-33-1.mol

Synonyms:Benzenesulfonicacid, 4-amino-3-nitro-, monosodium salt (9CI);Sulfanilic acid, 3-nitro-,sodium salt (6CI);Sodium 2-nitroaniline-4-sulfonate;Sodium 3-nitro-4-aminobenzenesulfonate;

Chemical Property of 2-NITROANILINE-4-SULFONIC ACID SODIUM SALT

Chemical Property:

• Appearance/Colour: yellow brown crystals
• Boiling Point: 99-100?°C11?mm Hg(lit.)
• Flash Point: 190?°F
• PSA: 137.42000
• Density: 0.99?g/mL?at 25?°C(lit.)
• LogP: 2.26630
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99.9% ^*data from raw suppliers

Sodium 2-Nitroaniline-4-sulfonate >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-NITROANILINE-4-SULFONIC ACID SODIUM SALT

There total 4 articles about 2-NITROANILINE-4-SULFONIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl<(4-chlorosulfonyl-2-nitro)phenyl>carbamate (84202-48-2) → sodium salt of 4-amino-3-nitrobenzenesulfonic acid (5042-33-1)

Guidance literature:

With hydrogenchloride; sodium hydroxide; Multistep reaction; 1.) ethanol, reflux, 4 h, 2.) water;

Reference yield:

N-carboethoxyaniline (101-99-5) → sodium salt of 4-amino-3-nitrobenzenesulfonic acid (5042-33-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 72 percent / chlorosulfonic acid / 3 h / 55 - 65 °C

2: NaNO₃, conc. H₂SO₄ / 3 h / 0 - 5 °C

3: 1.) aq. NaOH, 2.) hydrochloric acid / 1.) ethanol, reflux, 4 h, 2.) water

With hydrogenchloride; chlorosulfonic acid; sodium hydroxide; sodium nitrate; sulfuric acid;

Reference yield:

ethyl 4-(chlorosulfonyl)phenylcarbamate (21208-62-8) → sodium salt of 4-amino-3-nitrobenzenesulfonic acid (5042-33-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₃, conc. H₂SO₄ / 3 h / 0 - 5 °C

2: 1.) aq. NaOH, 2.) hydrochloric acid / 1.) ethanol, reflux, 4 h, 2.) water

With hydrogenchloride; sodium hydroxide; sodium nitrate; sulfuric acid;

upstream raw materials:

ethyl<(4-chlorosulfonyl-2-nitro)phenyl>carbamate

N-carboethoxyaniline

ethyl 4-(chlorosulfonyl)phenylcarbamate

N-(ethoxycarbonyl)-2-nitroaniline

Downstream raw materials:

4-amino-3-nitrobenzenesulfonyl chloride

Refernces