1,1,2,2-Tetramethoxypropane

Base Information

• Chemical Name: 1,1,2,2-Tetramethoxypropane
• CAS No.: 19255-83-5
• Molecular Formula: C7H16O4
• Molecular Weight: 164.202
• European Community (EC) Number: 960-243-1
• DSSTox Substance ID: DTXSID00513049
• Nikkaji Number: J1.132.038D
• Wikidata: Q82372600
• Mol file: 19255-83-5.mol

Synonyms:1,1,2,2-tetramethoxypropane;19255-83-5;Propane, 1,1,2,2-tetramethoxy-;SCHEMBL5274450;DTXSID00513049;AKOS026730109;CS-0223264;EN300-114550

Chemical Property of 1,1,2,2-Tetramethoxypropane

Chemical Property:

• XLogP3: 0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 164.10485899
• Heavy Atom Count: 11
• Complexity: 96.6

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C(OC)OC)(OC)OC

Technology Process of 1,1,2,2-Tetramethoxypropane

There total 8 articles about 1,1,2,2-Tetramethoxypropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

methanol (67-56-1) + D-fructose (470-23-5) → methyl glyoxal dimethylacetal (19255-83-5) + methyl lactate (547-64-8,2155-30-8) + 1,1,2-trimethoxy-2-propanol

Guidance literature:

With hierarchical Sn-Beta-H-0.3 zeolite; at 120 ℃; for 1h; under 3750.38 Torr; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/c6gc02437h

Reference yield:

D-Glucose (2280-44-6) → glycolic acid methyl ester (96-35-5) + methyl glyoxal dimethylacetal (19255-83-5) + methyl lactate (547-64-8,2155-30-8) + 2,2-dimethoxypropanal (18218-94-5)

Guidance literature:

With exfoliated layered stannosilicate University of Zaragoza-solid number 4; In methanol; at 160 ℃; for 20h; Reagent/catalyst; Overall yield = 58.5 percent; Autoclave;

DOI:10.1016/j.cattod.2020.03.064

Reference yield:

Sucrose (57-50-1) → glycolic acid methyl ester (96-35-5) + methyl glyoxal dimethylacetal (19255-83-5) + methyl lactate (547-64-8,2155-30-8) + 2,2-dimethoxypropanal (18218-94-5)

Guidance literature:

With exfoliated layered stannosilicate University of Zaragoza-solid number 4; In methanol; at 160 ℃; for 20h; Reagent/catalyst; Overall yield = 63.5 percent; Autoclave;

DOI:10.1016/j.cattod.2020.03.064

upstream raw materials:

methanol

Propargylic aldehyde

2-methoxyacrolein

dihydroxyacetone

Downstream raw materials:

methyl glyoxal bis(benzoylhydrazone)

Refernces

• 1、 Murillo, Beatriz,de la Iglesia, óscar,Rubio, César,Coronas, Joaquín,Téllez, Carlos. "Conversion of sugars to methyl lactate with exfoliated layered stannosilicate UZAR-S4". . p. 90 - 96. Retrieved 2020/04/27.
• 2、 Hayashi, Yukiko,Sasaki, Yoshiyuki. "Tin-catalyzed conversion of trioses to alkyl lactates in alcohol solution". . p. 2716 - 2718. Retrieved 2007/10/03.