6-iodo-1,2,3,4-tetrahydroquinoline

Base Information

• Chemical Name: 6-iodo-1,2,3,4-tetrahydroquinoline
• CAS No.: 193354-16-4
• Molecular Formula: C9H10IN
• Molecular Weight: 259.08700
• Mol file: 193354-16-4.mol

Synonyms:

Chemical Property of 6-iodo-1,2,3,4-tetrahydroquinoline

Chemical Property:

• Boiling Point: 324.9±31.0 °C(Predicted)
• PKA: 4.17±0.20(Predicted)
• PSA: 12.03000
• Density: 1.678±0.06 g/cm3(Predicted)
• LogP: 2.78730

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-iodo-1,2,3,4-tetrahydroquinoline

There total 2 articles about 6-iodo-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1,2,3,4-tetrahydroisoquinoline (635-46-1) → 6-iodo-1,2,3,4-tetrahydroquinoline (193354-16-4)

Guidance literature:

With dihydrogen peroxide; iodine; In water; at 20 ℃;

Reference yield:

6-iodoquinoline (13327-31-6) → 6-iodo-1,2,3,4-tetrahydroquinoline (193354-16-4)

Guidance literature:

With hydrogen; In toluene; at 100 ℃; for 5h; under 15001.5 Torr; Autoclave;

DOI:10.1039/c6ta09916e

upstream raw materials:

1,2,3,4-tetrahydroisoquinoline

6-iodoquinoline

Refernces

• 1、 Yun, Ruirui,Zhang, Beibei,Zhan, Feiyang,Du, Liting,Wang, Zhaoxu,Zheng, Baishu. "Cu Nanoclusters Anchored on the Metal-Organic Framework for the Hydrolysis of Ammonia Borane and the Reduction of Quinolines". supporting information. p. 12906 - 12911. Retrieved 2021/08/30.
• 2、 Zhang, Sai,Xia, Zhaoming,Ni, Ting,Zhang, Huan,Wu, Chao,Qu, Yongquan. "Tuning chemical compositions of bimetallic AuPd catalysts for selective catalytic hydrogenation of halogenated quinolines". . p. 3260 - 3266. Retrieved 2017/02/26.