1,2-Bis(diethylphosphino)ethane

Base Information

• Chemical Name: 1,2-Bis(diethylphosphino)ethane
• CAS No.: 6411-21-8
• Molecular Formula: C10H24P2
• Molecular Weight: 206.248
• Hs Code.: 29310099
• European Community (EC) Number: 633-196-7
• DSSTox Substance ID: DTXSID20214324
• Nikkaji Number: J304.210C
• Wikidata: Q83090149
• ChEMBL ID: CHEMBL70363
• Mol file: 6411-21-8.mol

Synonyms:1,2-Bis(diethylphosphino)ethane;6411-21-8;2-diethylphosphanylethyl(diethyl)phosphane;Bis(1,2-diethylphosphino)ethane;1,2-Bis-(diethylphosphino)-ethane;MFCD00015175;CHEMBL70363;SCHEMBL169184;DTXSID20214324;1,2-bis-(diethylphosphino)ethane;1,2-Bis(diethylphosphino)ethane, 97%;(CH3CH2)2PCH2CH2P(CH2CH3)2;FT-0730655;[2-(Diethylphosphino)ethyl](diethyl)phosphine #

Chemical Property of 1,2-Bis(diethylphosphino)ethane

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 0.0213mmHg at 25°C
• Refractive Index: 1.508-1.51
• Boiling Point: 259.1 °C at 760 mmHg
• Flash Point: 114.1 °C
• PSA: 27.18000
• Density: 0.884
• LogP: 4.02980
• Sensitive.: Air Sensitive
• Solubility.: It is soluble in organic solvents.
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 7
• Exact Mass: 206.13532476
• Heavy Atom Count: 12
• Complexity: 73.8

Purity/Quality:

98% ^*data from raw suppliers

1,2-Bis(diethylphosphino)ethane, 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,C
• Statements: 36/37/38-21/22-34
• Safety Statements: 36/37/39-26-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCP(CC)CCP(CC)CC
• Uses: It is used in chemical reaearch, organic Intermediates.

Technology Process of 1,2-Bis(diethylphosphino)ethane

There total 6 articles about 1,2-Bis(diethylphosphino)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ethylenebis(diethylchlorophosphonium) dichloride → depe (6411-21-8)

Guidance literature:

With lithium aluminium tetrahydride; sodium aluminum tetrahydride; sodium hydride; In tetrahydrofuran; at -78 - 20 ℃; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.201300787

Reference yield: 57.0%

Diethylphosphine (627-49-6) + ethylene dibromide (106-93-4) → depe (6411-21-8)

Guidance literature:

Diethylphosphine; With cesiumhydroxide monohydrate; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Molecular sieve; Inert atmosphere;

ethylene dibromide; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Inert atmosphere; Molecular sieve;

Reference yield:

1,2-bis(diethylphosphoryl)ethane (13337-10-5) → depe (6411-21-8)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 1 h / 20 °C / Inert atmosphere

2: sodium hydride; lithium aluminium tetrahydride; sodium aluminum tetrahydride / tetrahydrofuran / 1 h / -78 - 20 °C / Schlenk technique; Inert atmosphere

With lithium aluminium tetrahydride; oxalyl dichloride; sodium aluminum tetrahydride; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1002/adsc.201300787

upstream raw materials:

diethylchlorophosphine

1,2-dichloro-ethane

Diethylphosphine

ethylene dibromide

Downstream raw materials:

1,5-cis,cis-cyclooctadiene

Tetrofosmin

cobaltocene

(1,2-bis(diethylphosphino)ethane)Ni(CO)2

Refernces

• 1、 Doyle, Laurence R.,Heath, Alex,Low, Choon Heng,Ashley, Andrew E.. "A convenient synthetic protocol to 1,2-bis(dialkylphosphino)-ethanes". . p. 603 - 608. Retrieved 2014/05/20.
• 2、 -. "Process for the preparation of substituted aromatic compounds". . . Retrieved 2008/06/13.