5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid

Base Information

• Chemical Name: 5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid
• CAS No.: 19591-46-9
• Molecular Formula: C19H12O8
• Molecular Weight: 368.29400
• Hs Code.: 2918990090
• Mol file: 19591-46-9.mol

Synonyms:5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid;

Chemical Property of 5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid

Chemical Property:

• Boiling Point: 631.5±55.0 °C(Predicted)
• PKA: 3.20±0.20(Predicted)
• PSA: 124.04000
• Density: 1.491±0.06 g/cm3(Predicted)
• LogP: 2.01080

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid

There total 6 articles about 5,8-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimellitic Anhydride (552-30-7,145253-53-8) → 5,8-Diacetoxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid (19591-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / AlCl₃, NaCl / 2 h / 170 °C

2: 1.) K₂CO₃, 2.) NaOH, water / 1) dioxan, acetone; 2) dioxan

With sodium hydroxide; aluminium trichloride; water; potassium carbonate; sodium chloride;

DOI:10.1016/S0960-894X(97)00102-9

Reference yield:

1,4-dihydroxy-6-anthraquinonecarboxylic acid (19591-45-8) → 5,8-Diacetoxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid (19591-46-9)

Guidance literature:

With sodium hydroxide; water; potassium carbonate; Yield given. Multistep reaction; 1) dioxan, acetone; 2) dioxan;

DOI:10.1016/S0960-894X(97)00102-9

Reference yield:

hydroquinone (123-31-9,8027-02-9) → 5,8-Diacetoxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid (19591-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / AlCl₃, NaCl / 2 h / 170 °C

2: 1.) K₂CO₃, 2.) NaOH, water / 1) dioxan, acetone; 2) dioxan

With sodium hydroxide; aluminium trichloride; water; potassium carbonate; sodium chloride;

DOI:10.1016/S0960-894X(97)00102-9

upstream raw materials:

1,4-dihydroxy-6-anthraquinonecarboxylic acid

hydroquinone

trimellitic Anhydride

acetic anhydride

Refernces

• 1、 Carney, Stephen L.,Broadmore, Richard J.,Tomlinson, Rosemarie,Kingston, Ann,Gallagher, Peter T.,Owton, W. Martin,Miles, Martin V.,Brunavs, Michael,Smith, Colin W.,Hicks, Terry A.,Dobson, David R.,Steggles, David J.,Ambler, Samantha J.,Halliday, Kelly A.. "Anthraquinones related to rhein inhibit glucose uptake into chondrocytes, a mechanism for anti-osteoarthritis drugs?". . p. 817 - 822. Retrieved 2007/10/03.