Mercaptoacetic acid 2-methoxyethyl ester

Base Information

• Chemical Name: Mercaptoacetic acid 2-methoxyethyl ester
• CAS No.: 19788-48-8
• Molecular Formula: C5H10O3S
• Molecular Weight: 150.199
• Hs Code.: 2930909090
• Mol file: 19788-48-8.mol

Synonyms:mercapto-acetic acid,2-methoxyethyl ester;METHOXYETHYL THIOGLYCOLATE;Acetic acid, mercapto-, 2-methoxyethyl ester;thiolglycolic acid 2-methoxy-ethyl ester;2-Methoxyethyl sulfanylacetate;Methoxyethyl-thioglycolat;2-methoxyethyl 2-mercaptoacetate;2-methoxyethyl thioglycolate;Mercaptoessigsaeure-2-methoxy-aethylester;Acetic acid,mercapto-,2-methoxyethyl ester;

Chemical Property of Mercaptoacetic acid 2-methoxyethyl ester

Chemical Property:

• Boiling Point: 222.0±15.0 °C(Predicted)
• PKA: 7.88±0.10(Predicted)
• PSA: 74.33000
• Density: 1.112±0.06 g/cm3(Predicted)
• LogP: 0.10580

Purity/Quality:

99%, ^*data from raw suppliers

2-methoxyethyl2-sulfanylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Mercaptoacetic acid 2-methoxyethyl ester

There total 2 articles about Mercaptoacetic acid 2-methoxyethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-methoxy-ethanol (109-86-4,95507-80-5) + mercaptoacetic acid (68-11-1) → 2-methoxyethyl 2-mercaptoacetate (19788-48-8)

Guidance literature:

With sulfuric acid; In toluene; Reflux;

Reference yield:

2-methoxy-ethanol (109-86-4,95507-80-5) + Methyl thioglycolate (2365-48-2) → 2-methoxyethyl 2-mercaptoacetate (19788-48-8)

Guidance literature:

With sulfuric acid; at 80 ℃; for 5h;

Reference yield: 61.0%

2-methoxyethyl 2-mercaptoacetate (19788-48-8) + (E)-1-((1RS,2SR)-2,6,6-trimethylcyclohex-3-enyl)but-2-en-1-one (359865-01-3,41436-42-4,71048-82-3) → 2-methoxyethyl 2-((4-oxo-4-(2,6,6-trimethylcyclohex-3-en-1-yl)butan-2-yl)thio)acetate

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 45 ℃; for 12h;

upstream raw materials:

2-methoxy-ethanol

Methyl thioglycolate

mercaptoacetic acid

Downstream raw materials:

Thioglycolamide

Refernces

• 1、 -. "COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE PERFUMING MOLECULES". Page/Page column 25-26. . Retrieved 2013/10/08.