Benzylidene-octyl-amine

Base Information

• Chemical Name: Benzylidene-octyl-amine
• CAS No.: 20172-40-1
• Molecular Formula: C15H23N
• Molecular Weight: 217.354
• DSSTox Substance ID: DTXSID30335514
• Nikkaji Number: J159.700K
• Mol file: 20172-40-1.mol

Synonyms:Benzylidene-octyl-amine;N-octyl-1-phenylmethanimine;N-Benzylidene-N-octylamine;20172-40-1;SCHEMBL1880842;DTXSID30335514;N-[(Z)-phenylmethylidene]-1-octanamine

Chemical Property of Benzylidene-octyl-amine

Chemical Property:

• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 8
• Exact Mass: 217.183049738
• Heavy Atom Count: 16
• Complexity: 168

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCN=CC1=CC=CC=C1

Technology Process of Benzylidene-octyl-amine

There total 15 articles about Benzylidene-octyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

n-Octylamine (111-86-4) + benzyl alcohol (100-51-6,185532-71-2) → N-benzylidene-1-octaneamine (20172-40-1)

Guidance literature:

With [2,2]bipyridinyl; copper(l) iodide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In acetonitrile; at 25 - 30 ℃; for 12h;

DOI:10.1002/adsc.201200574

Reference yield: 90.0%

n-Octylamine (111-86-4) + benzyl alcohol (100-51-6,185532-71-2) → N-benzylidene-1-octaneamine (20172-40-1) + N-benzyl-N-octylamine (1667-16-9)

Guidance literature:

With C₄₈H₇₁IrN₂P₂; In toluene; at 135 ℃; for 24h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/ejic.201500900

Reference yield: 78.0%

n-Octylamine (111-86-4) + benzylamine (100-46-9) → N-benzylidene-1-octaneamine (20172-40-1)

Guidance literature:

With oxygen; iron(II) bromide; In neat (no solvent); at 110 ℃; for 18h; Green chemistry;

DOI:10.1007/s10562-016-1789-3

upstream raw materials:

n-Octylamine

benzaldehyde

benzyl alcohol

benzylamine

Downstream raw materials:

1-(N-(N^α,N^ε-di-Boc-Lys)-N-octylamino)methylbenzene

N-octyl-1-aminomethylbenzene hydrochloride

N-benzyl-N-octylamine

Refernces

• 1、 Adimurthy, Subbarayappa,Badhani, Gaurav,Joshi, Abhisek. "Ionic-Liquid-Catalyzed Synthesis of Imines, Benzimidazoles, Benzothiazoles, Quinoxalines and Quinolines through C?N, C?S, and C?C Bond Formation". . p. 6705 - 6716. Retrieved 2021/12/31.
• 2、 Wu, Shipeng,Zhang, Hao,Cao, Qiue,Zhao, Qihua,Fang, Wenhao. "Efficient imine synthesisviaoxidative coupling of alcohols with amines in an air atmosphere using a mesoporous manganese-zirconium solid solution catalyst". . p. 810 - 822. Retrieved 2021/02/26.