Cyclohexanecarboperoxoic acid, 1,1-dimethylethyl ester

Base Information

• Chemical Name: Cyclohexanecarboperoxoic acid, 1,1-dimethylethyl ester
• CAS No.: 20396-49-0
• Molecular Formula: C11H20O3
• Molecular Weight: 200.278
• Mol file: 20396-49-0.mol

Synonyms:

Chemical Property of Cyclohexanecarboperoxoic acid, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarboperoxoic acid, 1,1-dimethylethyl ester

There total 4 articles about Cyclohexanecarboperoxoic acid, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

tert.-butylhydroperoxide (75-91-2) + Cyclohexanecarboxylic acid (98-89-5) → t-butyl cyclohexanecarboperoxoate (20396-49-0)

Guidance literature:

tert.-butylhydroperoxide; Cyclohexanecarboxylic acid; In dichloromethane; water; at 0 ℃; for 0.166667h;

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; water; at 20 ℃; for 16h;

DOI:10.1021/acs.orglett.1c03366

Reference yield: 43.0%

tert.-butylhydroperoxide (75-91-2) + cyclohexanecarbaldehyde (2043-61-0) → t-butyl cyclohexanecarboperoxoate (20396-49-0) + Cyclohexanecarboxylic acid (98-89-5)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In water; at 40 ℃; for 24h;

DOI:10.1039/c1cc14602e

Reference yield:

tert.-butylhydroperoxide (75-91-2) + cyclohexanylcarbonyl chloride (2719-27-9) → t-butyl cyclohexanecarboperoxoate (20396-49-0)

Guidance literature:

With pyridine; In dichloromethane;

upstream raw materials:

tert.-butylhydroperoxide

cyclohexanylcarbonyl chloride

cyclohexanecarbaldehyde

Cyclohexanecarboxylic acid

Downstream raw materials:

tert-butoxy radical

cyclohexane carboxylate

4-cyanobenzaldehyde

4-nitrobenzoic acid methyl ester

Refernces

• 1、 Pérez-Palau, Marina,Sanosa, Nil,Romea, Pedro,Urpí, Fèlix,López, Rosa,Gómez-Bengoa, Enrique,Font-Bardia, Mercè. "Stereoselective Alkylation of Chiral Titanium(IV) Enolates with tert-Butyl Peresters". supporting information. p. 8852 - 8856. Retrieved 2021/11/17.
• 2、 Ye, Changqing,Qian, Bo,Li, Yajun,Su, Min,Li, Daliang,Bao, Hongli. "Iron-Catalyzed Dehydrative Alkylation of Propargyl Alcohol with Alkyl Peroxides to Form Substituted 1,3-Enynes". supporting information. p. 3202 - 3205. Retrieved 2018/06/11.