5-CHLORO-2-HYDROXY-BENZENESULPHONIC ACID

Base Information

• Chemical Name: 5-CHLORO-2-HYDROXY-BENZENESULPHONIC ACID
• CAS No.: 2051-65-2
• Molecular Formula: C6H5ClO4S
• Molecular Weight: 208.622
• Hs Code.: 2908999090
• Mol file: 2051-65-2.mol

Synonyms:5-chloro-2-hydroxy-benzenesulfonic Acid;4-Chlor-phenol-sulfonsaeure-(2);(2,5)-p-Chlorphenol-1-sulfonsaeure;2-hydroxy-5-chlorobenzenesulfonic acid;Benzenesulfonic acid,5-chloro-2-hydroxy;5-Chlor-2-hydroxy-benzolsulfonsaeure;

Chemical Property of 5-CHLORO-2-HYDROXY-BENZENESULPHONIC ACID

Chemical Property:

• PSA: 82.98000
• LogP: 2.37310

Purity/Quality:

98%min ^*data from raw suppliers

5-Chloro-2-hydroxybenzenesulfonicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-CHLORO-2-HYDROXY-BENZENESULPHONIC ACID

There total 6 articles about 5-CHLORO-2-HYDROXY-BENZENESULPHONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichlorobenzenesulfonic acid (88-42-6) → 2-hydroxy-5-chlorobenzenesulfonic acid (2051-65-2)

Guidance literature:

With alkali; at 170 - 190 ℃;

Reference yield:

4-chloro-phenol (106-48-9,82344-39-6) → 2-hydroxy-5-chlorobenzenesulfonic acid (2051-65-2) + 4-chloro-1-hydroxybenzene-5-sulfonic acid

Guidance literature:

With sulfur trioxide; In trichlorofluoromethane; at 10 ℃; for 0.5h;

DOI:10.1002/recl.19881070303

Reference yield:

4-chloro-phenol (106-48-9,82344-39-6) → 2-hydroxy-5-chlorobenzenesulfonic acid (2051-65-2)

Guidance literature:

With sulfuric acid; at 25 ℃; Rate constant; variation of H₂SO₄ concentration;

upstream raw materials:

2,5-dichlorobenzenesulfonic acid

sodium methylate

4-chloro-phenol

4-chloroanisole-2-sulfonic acid

Downstream raw materials:

4-chloro-2,6-dinitrophenol

5-chloro-2-hydroxy-3-nitro-benzenesulfonic acid

hydroquinone

2-hydroxyresorcinol

Refernces

• 1、 Wit, Peter de,Cerfontain, Hans. "Sulfonation of chloro- and dichloroanisoles with concentrated aqueous sulfuric acid and sulfur trioxide. Demethylation of chloroanisolesulfonic acids in sulfuric acid systems". . p. 418 - 425. Retrieved 2007/10/02.