Maytanacine

Base Information Edit

Chemical Name:Maytanacine
CAS No.:57103-69-2
Molecular Formula:C30H39 Cl N2 O9
Molecular Weight:607.1
Hs Code.:
ChEMBL ID:CHEMBL3245315
Mol file:57103-69-2.mol

Synonyms:MAYTANACINE;Ansamitocin P 1;NSC 239387;(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl acetate;C30-H39-Cl-N2-O9;ansamitocin P1;57103-69-2;Maytansine, O3-acetyl-O3-de(2-(acetylmethylamino)-1-oxopropyl)-;Maytansine, O3-acetyl-O3-de[2-(acetylmethylamino)-1-oxopropyl]-;CHEMBL3245315;SCHEMBL18494891;MQYZCKOGTWYJAZ-SRJPUCLNSA-N;5IJ

Suppliers and Price of Maytanacine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Maytanacine Edit

Chemical Property:

Vapor Pressure:5.28E-29mmHg at 25°C
Boiling Point:827.4°Cat760mmHg
Flash Point:454.2°C
PSA：136.16000
Density:1.33g/cm³
LogP:4.08130
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:606.2344085
Heavy Atom Count:42
Complexity:1100

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C)C)C)OC)(NC(=O)O2)O
Isomeric SMILES:C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)C)C)\C)OC)(NC(=O)O2)O

Technology Process of Maytanacine

There total 8 articles about Maytanacine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-24-7
acetic anhydride

: 57103-69-2
maytanacine

Guidance literature:: maytansinol; With lithium hexamethyldisilazane; In tetrahydrofuran; at -40 ℃; for 0.25h;

acetic anhydride; In tetrahydrofuran; at -40 ℃; for 2h;

With water; ammonium chloride; In tetrahydrofuran;

Reference yield:

: 64-19-7,77671-22-8
acetic acid

: 57103-68-1
maytansinol

: 57103-69-2
maytanacine

Guidance literature:: acetic acid; maytansinol; With dmap; scandium tris(trifluoromethanesulfonate); In dichloromethane; at -8 ℃; for 0.5h;

With diisopropyl-carbodiimide; In dichloromethane;