phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine

Base Information

• Chemical Name: phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine
• CAS No.: 5664-49-3
• Molecular Formula: C13H12N4S2
• Molecular Weight: 288.397
• NSC Number: 322033
• DSSTox Substance ID: DTXSID40317907
• Wikidata: Q82073007
• Mol file: 5664-49-3.mol

Synonyms:NSC322033;5664-49-3;NSC 322033;DTXSID40317907;NSC-322033;phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine

Chemical Property of phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine

Chemical Property:

• Boiling Point: 485.8°Cat760mmHg
• Flash Point: 247.6°C
• Density: 1.444g/cm³
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 288.05033875
• Heavy Atom Count: 19
• Complexity: 255

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(NC2=NC=CS2)NC3=NC=CS3

Technology Process of phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine

There total 3 articles about phenyl-N,N-di(1,3-thiazol-2-yl)methanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-thiazolylamine (96-50-4) + benzaldehyde (100-52-7) → benzene (5664-49-3)

Guidance literature:

at 100 ℃; for 0.5h; under 11.3 Torr;

DOI:10.1055/s-1991-26528

Reference yield:

2-thiazolylamine (96-50-4) + benzaldehyde (100-52-7) → benzene (5664-49-3) + benzylidene-1,3-thiazol-2-yl-amine (13243-76-0)

Guidance literature:

Yield given;

Reference yield:

2-thiazolylamine (96-50-4) + methanol (67-56-1) + benzaldehyde (100-52-7) → benzene (5664-49-3) + benzylidene-1,3-thiazol-2-yl-amine (13243-76-0) + (Methoxy-phenyl-methyl)-thiazol-2-yl-amine

Guidance literature:

Yield given. Yields of byproduct given;

upstream raw materials:

2-thiazolylamine

benzaldehyde

methanol

Downstream raw materials:

2-thiazolylamine

benzylidene-1,3-thiazol-2-yl-amine

2-fenil-3-(2-tiazolil)-4-tiazolidinone

Refernces

• 1、 Hopkinson,Meakins,Purcell. "Formation of azomethines from 2-aminothiazoles and (heterocyclic) aromatic aldehydes". . p. 621 - 624. Retrieved 2007/10/02.
• 2、 Boedeker, J.,Courault, K.. "Synthesis and Properties of Azomethines from α-Amino-N-heterocycles". . p. 336 - 342. Retrieved 2007/10/02.