20,22-Dihydrodigitoxigenin

Base Information Edit

Chemical Name:20,22-Dihydrodigitoxigenin
CAS No.:4427-85-4
Molecular Formula:C23H36O4
Molecular Weight:376.536
Hs Code.:
European Community (EC) Number:224-612-4
DSSTox Substance ID:DTXSID30963199
Nikkaji Number:J82.305H
Wikidata:Q76009928
ChEMBL ID:CHEMBL2068952
Mol file:4427-85-4.mol

Synonyms:20,22-dihydrodigitoxigenin

Suppliers and Price of 20,22-Dihydrodigitoxigenin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 20,22-Dihydrodigitoxigenin Edit

Chemical Property:

Melting Point:218-220°C
Boiling Point:540.5°Cat760mmHg
Flash Point:183.7°C
PSA：66.76000
Density:1.203g/cm³
LogP:3.68420
Storage Temp.:-20°C
Solubility.:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated)
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:376.26135963
Heavy Atom Count:27
Complexity:634

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(CC1CCC3C2CCC4(C3(CCC4C5CC(=O)OC5)O)C)O
Isomeric SMILES:C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4[C@H]5CC(=O)OC5)O)C)O
Uses 20,22-Dihydro-digitoxigenin can be used in the preparation of aminoalkylthio digitalis derivatives and to evaluate their receptor affinity. It is also used in a Free-?Wilson analysis of 5β-?14β-?androstane derivatives inhibiting the sodium-?potassium ATPase from human heart.

Technology Process of 20,22-Dihydrodigitoxigenin

There total 12 articles about 20,22-Dihydrodigitoxigenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143-62-4
(+)-digitoxigenin

: 4427-85-4
3β,14β-dihydroxy-5β-20(R)-cardanolide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine

2: 66.2 percent / H₂ / PtO₂ / ethanol / 24 h

3: 0.5 n KOH / methanol / 49 h / Ambient temperature

With potassium hydroxide; hydrogen; platinum(IV) oxide; In pyridine; methanol; ethanol;

Reference yield:

: 808-19-5
digitoxigenin 3-acetate

: 4427-85-4
3β,14β-dihydroxy-5β-20(R)-cardanolide

Guidance literature:: Multi-step reaction with 2 steps

1: 66.2 percent / H₂ / PtO₂ / ethanol / 24 h

2: 0.5 n KOH / methanol / 49 h / Ambient temperature

With potassium hydroxide; hydrogen; platinum(IV) oxide; In methanol; ethanol;