4-oxo-N-phenylpentanamide

Base Information

• Chemical Name: 4-oxo-N-phenylpentanamide
• CAS No.: 23132-35-6
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Hs Code.: 2924299090
• Mol file: 23132-35-6.mol

Synonyms:4-oxopentan-N-phenylamide;N-phenyl 4-oxo-pentanamide;Laevulinanilid;Pentanamide,4-oxo-N-phenyl;Levulinanilide;Laevulinsaeure-anilid;4-Oxo-valeriansaeure-anilid;4-oxo-N-phenylpentaneamide;

Chemical Property of 4-oxo-N-phenylpentanamide

Chemical Property:

• PSA: 49.66000
• LogP: 2.64380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-oxo-N-phenylpentanamide

There total 10 articles about 4-oxo-N-phenylpentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

diiodomethane (75-11-6) + N-phenylacetoacetamide (102-01-2,98624-45-4) → levulinanilide (23132-35-6)

Guidance literature:

diiodomethane; With diethylzinc; In hexane; dichloromethane; at 0 ℃; for 0.166667h;

N-phenylacetoacetamide; In hexane; dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)00879-1

Reference yield:

levulinic acid (123-76-2) + aniline (62-53-3) → levulinanilide (23132-35-6)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 23 ℃;

DOI:10.1016/j.ejmech.2016.05.025

Reference yield:

4-pentynoic acid (6089-09-4) + aniline (62-53-3) → levulinanilide (23132-35-6)

Guidance literature:

With potassium tetrachloroaurate(III); In neat (no solvent); at 50 ℃; for 3h; Reagent/catalyst;

DOI:10.1021/acscatal.7b02183

upstream raw materials:

5-methyl-2-furanone

aniline

N-phenylmaleimide

methylmagnesium bromide

Downstream raw materials:

(E)-4-phenyliminopentan-N-phenylamide

5-methyl-1-phenylpyrrolidin-2-one

N-phenyl 4-hydroxypentanamide

2-methyl-1-phenyl-1H-pyrrole

Refernces

• 1、 Joshi, Shrinivas D.,Kumar, Devendra,Dixit, Sheshagiri R.,Tigadi, Nageshwar,More, Uttam A.,Lherbet, Christian,Aminabhavi, Tejraj M.,Yang, Kap Seung. "Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes". . p. 21 - 39. Retrieved 2016/08/19.