Technology Process of 6-Hydroxyisobergapten
There total 6 articles about 6-Hydroxyisobergapten which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
Lindlar's catalyst;
In
tetrahydrofuran;
for 2h;
Yield given;
DOI:10.1021/jo00253a002
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) n-butyllithium / 1.) THF, -78 deg C, 5 min, 2.) -78 deg C, 15 min
2: aq. ceric ammonium nitrate (CAN), / acetonitrile / 0.25 h / 0 °C
3: H2 / 5percent Pd/CaCO3 (Pb poisoned) / tetrahydrofuran / 2 h
With
n-butyllithium; ammonium cerium(IV) nitrate; hydrogen;
Lindlar's catalyst;
In
tetrahydrofuran; acetonitrile;
DOI:10.1021/jo00253a002
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 18-crown-6, K2CO3 / toluene / 12 h / 60 °C
2: 1.) aq. AgNO3 2.) aq. KCN / 1.) ethanol, 45 min. 2.) 1.5 h
3: 1.) n-butyllithium / 1.) THF, -78 deg C, 5 min, 2.) -78 deg C, 15 min
4: aq. ceric ammonium nitrate (CAN), / acetonitrile / 0.25 h / 0 °C
5: H2 / 5percent Pd/CaCO3 (Pb poisoned) / tetrahydrofuran / 2 h
With
potassium cyanide; n-butyllithium; ammonium cerium(IV) nitrate; 18-crown-6 ether; hydrogen; potassium carbonate; silver nitrate;
Lindlar's catalyst;
In
tetrahydrofuran; toluene; acetonitrile;
DOI:10.1021/jo00253a002
