N-Nitroso-N-benzylacetamide

Base Information

• Chemical Name: N-Nitroso-N-benzylacetamide
• CAS No.: 10575-97-0
• Molecular Formula: C9H10 N2 O2
• Molecular Weight: 178.191
• Hs Code.: 2924299090
• Mol file: 10575-97-0.mol

Synonyms:Acetamide,N-benzyl-N-nitroso- (6CI,7CI,8CI); N-Benzyl-N-nitrosoacetamide

Chemical Property of N-Nitroso-N-benzylacetamide

Chemical Property:

• Vapor Pressure: 0.00481mmHg at 25°C
• Boiling Point: 276.4°Cat760mmHg
• Flash Point: 121°C
• PSA: 49.74000
• Density: 1.12g/cm³
• LogP: 1.71650

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Nitroso-N-benzylacetamide

There total 4 articles about N-Nitroso-N-benzylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(phenylmethyl)acetamide (588-46-5) → N-benzyl-N-nitrosoacetamide (10575-97-0)

Guidance literature:

With sodium acetate; dinitrogen tetraoxide; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1021/jo990494m

Reference yield: 8.0%

N-Nitroso-N-benzylformamide (85995-49-9) + acetyl chloride (75-36-5) → N-benzyl-N-nitrosoacetamide (10575-97-0) + Benzyl acetate (140-11-4) + benzyl formate (104-57-4) + benzyl chloride (100-44-7) + 1,1'-(1,2-ethanediyl)bisbenzene (103-29-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Product distribution; 1) -5 degC, 1h, 2) room temp., overnight;

DOI:10.1021/jo00163a012

Reference yield:

C10H10N2O2 (80326-66-5) → N-benzyl-N-nitrosoacetamide (10575-97-0) + Benzyl acetate (140-11-4) + benzyl pyruvate (18854-19-8) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With ozone; In dichloromethane; at -78 ℃; Yield given. Further byproducts given;

DOI:10.1021/ja00324a067

upstream raw materials:

N-(phenylmethyl)acetamide

C₁₀H₁₀N₂O₂

N-Nitroso-N-benzylformamide

acetyl chloride

Downstream raw materials:

Diphenylmethane

2-benzyltoluene

Benzyl acetate

1-methyl-4-(phenylmethyl)benzene

Refernces

• 1、 Darbeau, Ron W.,White, Emu H.,Song, Fenhong,Darbeau, Nyla R.,Chou, James. "A Study of Essentially Free Carbocations Derived via Diazonium and Oxo Diazonium Ions in the Liquid Phase". . p. 5966 - 5978. Retrieved 2007/10/03.
• 2、 White,Egger. "Reaction of sydnones with ozone as a method of deamination: On the mechanism of inhibition of monoamine oxidase by sydnones". . p. 3701 - 3703. Retrieved 2007/10/02.