2,3-diphenyl-6-quinoxalinyl methyl ether

Base Information

• Chemical Name: 2,3-diphenyl-6-quinoxalinyl methyl ether
• CAS No.: 26832-42-8
• Molecular Formula: C21H16N2O
• Molecular Weight: 312.371
• Mol file: 26832-42-8.mol

Synonyms:6-Methoxy-2,3-diphenyl-quinoxaline;2,3-diphenyl-7-methoxyquinoxaline;2,3-diphenyl-6-methoxyquinoxaline;6-Methoxy-2,3-diphenyl-chinoxalin;2,3-Diphenyl-6-methoxychinoxalin;

Chemical Property of 2,3-diphenyl-6-quinoxalinyl methyl ether

Chemical Property:

• PSA: 35.01000
• LogP: 4.97240

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-diphenyl-6-quinoxalinyl methyl ether

There total 20 articles about 2,3-diphenyl-6-quinoxalinyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzil (134-81-6) + 4-methoxy-1,2-phenylenediamine (102-51-2) → 6-methoxy-2,3-diphenylquinoxaline (26832-42-8)

Guidance literature:

In methanol; acetic acid; at 160 ℃; for 0.0833333h; Irradiation;

DOI:10.1016/j.tetlet.2004.04.144

Reference yield: 97.0%

phenyl benzyl ketone (451-40-1) + 4-methoxy-1,2-phenylenediamine (102-51-2) → 6-methoxy-2,3-diphenylquinoxaline (26832-42-8)

Guidance literature:

With oxygen; triethylamine; In toluene; at 90 ℃; for 12h; under 760.051 Torr;

DOI:10.1016/j.tet.2012.03.020

Reference yield: 97.0%

benzil (134-81-6) + 4-methoxy-2-nitroaniline (96-96-8) → 6-methoxy-2,3-diphenylquinoxaline (26832-42-8)

Guidance literature:

With tin(ll) chloride; In ethanol; water; for 0.333333h; Reflux;

DOI:10.1002/jhet.5570450637

upstream raw materials:

benzil

4-methoxy-1,2-phenylenediamine

(E)-3-methoxy-N-(phenylmethylene)benzenamine

phenylacetylene

Downstream raw materials:

2,3-diphenylquinoxaline-6-ol

Refernces

• 1、 Bhuvanesh, Nattamai,Gopiraman, Mayakrishnan,Karvembu, Ramasamy,Sindhuja, Dharmalingam,Vasanthakumar, Punitharaj. "Ruthenium?p-cymene complexes with acylthiourea, and its heterogenized form on graphene oxide act as catalysts for the synthesis of quinoxaline derivatives". . . Retrieved 2021/06/30.
• 2、 Shee, Sujan,Panja, Dibyajyoti,Kundu, Sabuj. "Nickel-Catalyzed Direct Synthesis of Quinoxalines from 2-Nitroanilines and Vicinal Diols: Identifying Nature of the Active Catalyst". . p. 2775 - 2784. Retrieved 2020/03/13.