Hydroquinidine hydrochloride

Base Information

• Chemical Name: Hydroquinidine hydrochloride
• CAS No.: 1476-98-8
• Molecular Formula: C20H27ClN2O2
• Molecular Weight: 362.9
• European Community (EC) Number: 216-024-1
• UNII: 6BR4G8VAHM
• ChEMBL ID: CHEMBL533007
• DSSTox Substance ID: DTXSID00933162
• Mol file: 1476-98-8.mol

Synonyms:dihydroquinidine;dihydroquinine;hydroquinidine;hydroquinidine dihydrochloride, (1beta,4beta,3S)-(+-)-isomer;hydroquinidine dihydrochloride, (3alpha,9S)-(+-)-isomer;hydroquinidine hydrochloride;hydroquinidine monosulfate;hydroquinidine monosulfate, (1beta,3alpha,4beta,8alpha,9R)-isomer;hydroquinidine monosulfate, (1beta,3alpha,4beta,9S)-isomer;hydroquinidine sulfate;hydroquinidine sulfate, (9S)-isomer;hydroquinidine, (+-)-isomer;hydroquinidine, (1beta, 3alpha,4beta,8alpha,9R)-isomer;hydroquinidine, (1beta,3alpha,4beta,9S)-isomer;hydroquinidine, (1beta,4beta,9S)-(+-)-isomer;hydroquinidine, (3alpha,9S)-(+-)-isomer;hydroquinidine, (8alpha,9R)-isomer;hydroquinidine, (8alpha,9S)-isomer;hydroquinidine, (9R)-isomer;hydroquinidine, (9S)-(+-)-isomer;hydroquinine;LCN 834;LCN-834;Lentoquine;Sérécor

Chemical Property of Hydroquinidine hydrochloride

Chemical Property:

• Vapor Pressure: 9.92E-12mmHg at 25°C
• Melting Point: 277-279 °C(lit.)
• Refractive Index: 188 ° (C=1.3, H2O)
• Boiling Point: 522.1 °C at 760 mmHg
• Flash Point: 269.6 °C
• PSA: 45.59000
• Density: 1.2 g/cm³
• LogP: 4.13710
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: almost transparency in hot Water
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 362.1761058
• Heavy Atom Count: 25
• Complexity: 432

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hydroquinidine HCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-20/21/22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC1CN2CCC1CC2C(C3=C4C=C(C=CC4=NC=C3)OC)O.Cl
• Isomeric SMILES: CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](C3=C4C=C(C=CC4=NC=C3)OC)O.Cl
• Recent EU Clinical Trials: Evaluation de l'intérêt d'un traitement par hydroquinidine pour la prise en charge des patients atteints d'un syndrome de Brugada à risque rythmique élevé et implantés d'un défibrillateur