PARACETAMOL SULFATE POTASSIUM SALT

Base Information

• Chemical Name: PARACETAMOL SULFATE POTASSIUM SALT
• CAS No.: 32113-41-0
• Molecular Formula: C8H9 N O5 S . K
• Molecular Weight: 269.32
• Hs Code.: 2924299090
• Mol file: 32113-41-0.mol

Synonyms:Acetamide,N-[4-(sulfooxy)phenyl]-, monopotassium salt (9CI); Acetanilide, 4'-hydroxy-,hydrogen sulfate (ester), monopotassium salt (8CI); PotassiumN-acetyl-p-aminophenyl sulfate

Chemical Property of PARACETAMOL SULFATE POTASSIUM SALT

Chemical Property:

• Melting Point: 163 °C
• PSA: 103.91000
• LogP: 1.63780
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble

Purity/Quality:

98%Min ^*data from raw suppliers

4-AcetaminophenSulfatePotassiumSalt ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 37/38-41-43
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Acetaminophen sulfate is an inactive metabolite of the antipyretic and analgesic agent acetaminophen . It is formed from acetaminophen via the sulfotransferase (SULT) isoforms SULT2A1, SULT1E1, SULT1A1, SULT1A3, and SULT1A4.
• Uses: A metabolite of Acetaminophen A metabolite of 4-Acetaminophen (Paracetamol) as blood platelet aggregation inhibitor. Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

Technology Process of PARACETAMOL SULFATE POTASSIUM SALT

There total 2 articles about PARACETAMOL SULFATE POTASSIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-acetaminophenol (103-90-2,8055-08-1) → potassium 4-acetamidophenylsulfate monoester (32113-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / Heating

2: aq. KOH

With potassium hydroxide; In toluene;

DOI:10.1039/b513712h

Reference yield:

Acetaminophen sulfate (10066-90-7) → potassium 4-acetamidophenylsulfate monoester (32113-41-0)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/b513712h

Reference yield:

sulfuric acid (7664-93-9) + potassium 4-acetamidophenylsulfate monoester (32113-41-0) → 4-amino-phenol (123-30-8) + acetic acid (64-19-7,77671-22-8)

Guidance literature:

at 120 ℃;

upstream raw materials:

Acetaminophen sulfate

4-acetaminophenol

Downstream raw materials:

4-amino-phenol

acetic acid

Refernces