MORPHOLINE-3 5-DIONE 97

Base Information

• Chemical Name: MORPHOLINE-3 5-DIONE 97
• CAS No.: 4430-05-1
• Molecular Formula: C4H5 N O3
• Molecular Weight: 115.089
• Hs Code.: 2934999090
• Mol file: 4430-05-1.mol

Synonyms:Diglycolimide(6CI); NSC 631634

Chemical Property of MORPHOLINE-3 5-DIONE 97

Chemical Property:

• Melting Point: 142-145 °C(lit.)
• PSA: 55.40000
• LogP: -1.01180

Purity/Quality:

98.5% ^*data from raw suppliers

Morpholine-3 5-Dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of MORPHOLINE-3 5-DIONE 97

There total 3 articles about MORPHOLINE-3 5-DIONE 97 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,2'-oxybis-acetic acid (110-99-6) → morpholine-3,5-dione (4430-05-1)

Guidance literature:

With ammonium carbonate; at 230 ℃; for 5h;

DOI:10.1016/S0040-4020(97)00924-1

Reference yield:

1,4-dioxane-2,6-dione (4480-83-5) → morpholine-3,5-dione (4430-05-1)

Guidance literature:

With ammonium hydroxide; Heating;

DOI:10.1016/S0040-4020(01)96568-8

Reference yield:

→ morpholine-3,5-dione (4430-05-1)

Guidance literature:

bei der Destillation;

upstream raw materials:

2,2'-oxybis-acetic acid

1,4-dioxane-2,6-dione

Downstream raw materials:

4-Cyclohex-3-enylmethyl-morpholine-3,5-dione

2-(2-amino-2-oxoethoxy)acetic acid

4-(2-{[5-Bromo-2-({3-chloro-4-[(2-methylphenyl)carbonyl]phenyl}amino)benzyl]oxy}ethyl)morpholine-3,5-dione

4-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)morpholine-3,5-dione

Refernces

• 1、 Aitken,Farrell,Kirton. "Synthesis and pyrolysis of tetrahydro-1,4-oxazine-3,5-diones and tetrahydro-1,4-thiazine-3,5-diones". . p. 1526 - 1531. Retrieved 2007/10/03.
• 2、 Vliet, P. N. W. Van Der,Hamersma, J. A. M.,Speckamp, W. N.. "CYCLISATIONS OF 1,3-THIAZINE-2,4-DIONES AND RELATED SYSTEMS". . p. 2007 - 2014. Retrieved 2007/10/02.