2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE

Base Information

• Chemical Name: 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE
• CAS No.: 31980-12-8
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.18800
• Mol file: 31980-12-8.mol

Synonyms:2.2-Dimethyl-2H-benzimidazol-1,3-dioxid;2,2-dimethyl-2H-benzoimidazole 1,3-dioxide;2,2-dimethyl-2H-benzimidazole-1,3-dioxide;2,2-Dimethyl-2H-benzimidazol 1,3-dioxid;2,2-Dimethylisobenzimidazol-1,3-dioxid;2,2-dimethyl-2H-benzimidazole 1,3-dioxide;

Chemical Property of 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE

Chemical Property:

• Melting Point: 122 - 123 °C
• PSA: 57.50000
• LogP: -0.38630

Purity/Quality:

99% ^*data from raw suppliers

2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE

There total 15 articles about 2,2-DIMETHYL-2H-1,3-BENZIMIDAZOLEDIIUM-1,3-DIOLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzofurazan oxide (480-96-6,68100-26-5) + 2-nitropropane (79-46-9) → 2,2-dimethyl-2H-benzimidazole 1,3-dioxide (31980-12-8)

Guidance literature:

With piperidine; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm0600343

Reference yield: 81.0%

o-benzoquinone-1,2-dioxime (14208-17-4) + acetone (67-64-1) → 2,2-dimethyl-2H-benzimidazole 1,3-dioxide (31980-12-8)

Guidance literature:

With perchloric acid; In methanol; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2017.05.078

Reference yield: 75.0%

benzofurazan oxide (480-96-6,68100-26-5) + isopropyl alcohol (67-63-0,8013-70-5) → 2,2-dimethyl-2H-benzimidazole 1,3-dioxide (31980-12-8)

Guidance literature:

With sulfuric acid; for 2h; Ambient temperature;

DOI:10.1007/BF01169943

upstream raw materials:

potassium acetate

4,7-dibromo-2,2-dimethyl-4,5,6,7-tetrahydro-2H-benzimidazole 1,3-dioxide

4,7-dibromo-2,2-dimethylcyclohepta-2H-imidazole 1,3-dioxide

o-benzoquinone-1,2-dioxime

Refernces

• 1、 Chugunova, Elena,Samsonov, Vladimir,Gerasimova, Tatiana,Rybalova, Tatiana,Bagryanskaya, Irina. "Synthesis and some properties of 2H-benzimidazole 1,3-dioxides". . p. 7233 - 7244. Retrieved 2015.
• 2、 Chugunova, Elena,Samsonov, Vladimir,Akylbekov, Nurgali,Mazhukin, Dmitrii. "Synthesis of 2H-benzimidazole 1,3-dioxides, separase inhibitors, by reaction of o-benzoquinone dioximes with ketones". . p. 3986 - 3992. Retrieved 2017/06/13.