1-(1-naphthyl)ethylamine

Base Information

• Chemical Name: 1-(1-naphthyl)ethylamine
• CAS No.: 3309-13-5
• Molecular Formula: C₁₂H₁₃N
• Molecular Weight: 171.242
• Mol file: 3309-13-5.mol

Synonyms:Indeloxazine hydrochloride (R)-form [MI];Indeloxazine hydrochloride,(R);Morpholine,2-((1H-inden-7-yloxy)methyl)-,hydrochloride (1:1),(2R);(+)-1-naphthalen-1-yl-ethylamine;(+)-1-(1-naphthyl)ethylamine;(+)-1-(1-Naphthyl)ethylamin;(+)-indeloxazine hydrochloride;UNII-15QZ6NE84E component KEBHLNDPKPIPLI-UTONKHPSSA-N;

Chemical Property of 1-(1-naphthyl)ethylamine

Chemical Property:

• PSA: 26.02000
• LogP: 3.55980

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(1-naphthyl)ethylamine

There total 1 articles about 1-(1-naphthyl)ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(RS)-1-(1-naphthyl)ethylamine (42882-31-5) → (+)-α-1-(naphthyl)-ethylamine (3309-13-5,3886-70-2,10420-89-0,42882-31-5)

Guidance literature:

With triethylamine; In dichloromethane; for 0.166667h; Ambient temperature;

DOI:10.1246/cl.1982.745

Reference yield: 54.0%

succinic acid anhydride (108-30-5) + (+)-α-1-(naphthyl)-ethylamine (3309-13-5,3886-70-2,10420-89-0,42882-31-5) → (+)-3-<1-(1-Naphthyl)ethylcarbamoyl>propionsaeure (78681-09-1)

Guidance literature:

With triethylamine; In chloroform; for 2h; Heating;

Reference yield:

(S)-4-Ethyl-4-hydroxy-tetrahydro-pyran-2-one (72165-48-1) + (+)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride (20445-33-4) + (+)-α-1-(naphthyl)-ethylamine (3309-13-5,3886-70-2,10420-89-0,42882-31-5) → (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-3-hydroxy-3-[((R)-1-naphthalen-1-yl-ethylcarbamoyl)-methyl]-pentyl ester

Guidance literature:

In pyridine; Heating;

DOI:10.1039/c39830000268

upstream raw materials:

(RS)-1-(1-naphthyl)ethylamine

Downstream raw materials:

(+)-3-<1-(1-Naphthyl)ethylcarbamoyl>propionsaeure

Refernces

• 1、 Jurczak, Janusz,Krawczyk, Zbigniew. "(-)-ω-CAMPHANIC ACID AS A CONVENIENT REAGENT FOR RESOLUTION OF RACEMIC AMINES". . p. 2625 - 2627. Retrieved 2007/10/02.