Technology Process of Butanoic acid, 2-[(4-methoxy-3-nitrophenyl)methylene]-, ethyl ester
There total 1 articles about Butanoic acid, 2-[(4-methoxy-3-nitrophenyl)methylene]-, ethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
triethyl 2-ethylphosphonoacetate;
With
sodium hydride;
In
tetrahydrofuran;
for 1h;
4-methoxy-3-nitrobenzaldehyde;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
DOI:10.1021/jm0205144
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol;
under 2207.43 Torr;
DOI:10.1021/jm0205144
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 94 percent / H2 / Pd/C / tetrahydrofuran; ethanol / 2207.43 Torr
2: 1-[3-(dimethylaminopropyl)]-3-ethylcarbodiimide HCl salt / CH2Cl2 / 20 °C
3: aq. NaOH / ethanol / 4 h / 50 °C
With
sodium hydroxide; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm0205144
