Trimethylsulfonium iodide

Base Information

• Chemical Name: Trimethylsulfonium iodide
• CAS No.: 2181-42-2
• Deprecated CAS: 1232233-67-8
• Molecular Formula: C3H9S^.I
• Molecular Weight: 204.075
• Hs Code.: 29309070
• European Community (EC) Number: 218-555-4
• NSC Number: 36713
• UNII: 4Z1LIZ2LUN
• DSSTox Substance ID: DTXSID30883803
• Wikidata: Q2453392
• ChEMBL ID: CHEMBL25340
• Mol file: 2181-42-2.mol

Synonyms:trimethylsulfonium;trimethylsulfonium chloride;trimethylsulfonium hydroxide;trimethylsulfonium iodide;trimethylsulfonium nitrate;trimethylsulphonium chloride

Chemical Property of Trimethylsulfonium iodide

Chemical Property:

• Appearance/Colour: white to yellowish crystalline solid
• Melting Point: 215-220 °C(lit.)
• PSA: 25.30000
• Density: 1.6554 (estimate)
• LogP: -2.50190
• Storage Temp.: Store below +30°C.
• Sensitive.: Light Sensitive
• Solubility.: 400g/l
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 203.94697
• Heavy Atom Count: 5
• Complexity: 8

Purity/Quality:

99% ^*data from raw suppliers

Trimethylsulfonium Iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Sulfur Compounds
• Canonical SMILES: C[S+](C)C.[I-]
• Uses: Trimethylsulfonium iodide is a salt that is usually dissolved in strong base in order to synthesize epoxides in-situ. Trimethylsulfonium iodide also has the potential to inhibit human placental diamine oxidase.

Technology Process of Trimethylsulfonium iodide

There total 70 articles about Trimethylsulfonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methylthiol (74-93-1) + methyl iodide (74-88-4) → trimethylsulphonium iodide (2181-42-2)

Guidance literature:

In chloroform; for 5h; Ambient temperature;

DOI:10.1021/jo9620977

Reference yield: 96.0%

dimethylsulfide (75-18-3) + diiodomethane (75-11-6) → trimethylsulphonium iodide (2181-42-2)

Guidance literature:

In acetonitrile; at 50 ℃; for 168h;

DOI:10.1021/jo000015f

Reference yield: 90.0%

dimethylsulfide (75-18-3) + methyl iodide (74-88-4) → trimethylsulphonium iodide (2181-42-2)

Guidance literature:

In ethanol; for 24h; Ambient temperature;

DOI:10.1021/ja00344a038

upstream raw materials:

dimethylsulfide

acetyl iodide

ethanol

dimethyl-ethylsulphonium iodide

Downstream raw materials:

dimethylsulfide

methyl iodide

6-methyl-1-oxa-6-azaspiro<2.5>octane

2-(4-chloro-trans-styryl)-6,8-dimethyl-4-oxiranyl-quinoline

Refernces

• 1、 Kaltzoglou, Andreas,Stoumpos, Constantinos C.,Kontos, Athanassios G.,Manolis, Georgios K.,Papadopoulos, Kyriakos,Papadokostaki, Kyriaki G.,Psycharis, Vasilis,Tang, Chiu C.,Jung, Young-Kwang,Walsh, Aron,Kanatzidis, Mercouri G.,Falaras, Polycarpos. "Trimethylsulfonium Lead Triiodide: An Air-Stable Hybrid Halide Perovskite". . p. 6302 - 6309. Retrieved 2017.
• 2、 Steinkopf,Mueller,S.. "-". . p. 1928. Retrieved 1923.
• 3、 Fischer, Stefan,Huwyler, Nikolas,Wolfrum, Susanne,Carreira, Erick M.. "Synthesis and Biological Evaluation of Bromo- and Fluorodanicalipin A". . p. 2555 - 2558. Retrieved 2016.
• 4、 Sorokin,Voronkov. "Reactions of (triethylstannylthioalkyl)trialkoxysilanes and (triethylstannylthioalkyl)trialkoxysilatranes with methyl iodide". . p. 2056 - 2060. Retrieved 2008.
• 5、 Kaltzoglou, Andreas,Elsenety, Mohamed M.,Koutselas, Ioannis,Kontos, Athanassios G.,Papadopoulos, Kyriakos,Psycharis, Vassilis,Raptopoulou, Catherine P.,Perganti, Dorothea,Stergiopoulos, Thomas,Falaras, Polycarpos. "Synthesis, characterization and optoelectronic properties of chemically stable (CH3)3SPbI3?xBrx and (CH3)3SPbI3?xClx (x?=?0, 1, 2, 3) perovskites". . p. 67 - 73. Retrieved 2018.
• 6、 -. "Method for preparing naproxen intermediate". Paragraph 0095-0100. . Retrieved 2020/12/08.