Technology Process of Benzaldehyde, 2,6-dimethoxy-4-pentyl-
There total 7 articles about Benzaldehyde, 2,6-dimethoxy-4-pentyl- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,3-dimethoxy-5-pentylbenzene;
With
N,N,N,N,-tetramethylethylenediamine;
In
tetrahydrofuran;
at -78 ℃;
Inert atmosphere;
With
sec.-butyllithium;
In
tetrahydrofuran; hexane;
at -78 - 0 ℃;
for 1.66667h;
Inert atmosphere;
N,N-dimethyl-formamide;
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 1.53333h;
Inert atmosphere;
DOI:10.1021/acs.orglett.7b03668
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / K2CO3 / acetone / 4 h / 60 °C
2: 83 percent / BuLi / tetrahydrofuran; hexane / 3 h / Heating
With
n-butyllithium; potassium carbonate;
In
tetrahydrofuran; hexane; acetone;
DOI:10.1021/ol063022k
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 90 percent / tetrahydrofuran; hexane / 1 h / -78 - 20 °C
2.1: 74 percent / p-toluenesulfonic acid / toluene / 1 h / Heating
3.1: 80 percent / H2 / Pd/C / methanol / 20 h / 20 °C
4.1: tetramethylethylenediamine; n-BuLi / diethyl ether; hexane / 2 h / 20 °C
4.2: 79 percent / diethyl ether; hexane / 4 h / 20 °C
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; hydrogen; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; hexane; toluene;
DOI:10.1055/s-2005-870008