12-(bromomethyl)benzo[a]acridine

Base Information

• Chemical Name: 12-(bromomethyl)benzo[a]acridine
• CAS No.: 34331-96-9
• Molecular Formula: C18H12BrN
• Mol file: 34331-96-9.mol

Synonyms:

Chemical Property of 12-(bromomethyl)benzo[a]acridine

Chemical Property:

• Vapor Pressure: 4.84E-10mmHg at 25°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12-(bromomethyl)benzo[a]acridine

There total 2 articles about 12-(bromomethyl)benzo[a]acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

9-methylbenz[a]acridine (3340-93-0) → 12-(bromomethyl)benzo[a]acridine (34331-96-9)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 2h; Reflux; Inert atmosphere;

DOI:10.1039/c3ob42600a

Reference yield:

N-Phenyl-2-naphthylamine (135-88-6,84420-28-0) → 12-(bromomethyl)benzo[a]acridine (34331-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: zinc(II) chloride / 180 °C / Inert atmosphere

1.2: 5 h / 250 °C / Inert atmosphere

2.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 2 h / Reflux; Inert atmosphere

With N-Bromosuccinimide; zinc(II) chloride; dibenzoyl peroxide; In tetrachloromethane;

DOI:10.1039/c3ob42600a

Reference yield: 82.0%

12-(bromomethyl)benzo[a]acridine (34331-96-9) + p-Toluic acid (99-94-5) → (benzo[a]acridin-12-yl)methyl 4-methylbenzoate (1609956-61-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 - 55 ℃; for 12h; Quantum yield; Inert atmosphere;

DOI:10.1039/c3ob42600a

upstream raw materials:

N-Phenyl-2-naphthylamine

9-methylbenz[a]acridine

Downstream raw materials:

(benzo[a]acridin-12-yl)methyl 2-phenylacetate

(benzo[a]acridin-12-yl)methyl benzoate

(benzo[a]acridin-12-yl)methyl 4-methylbenzoate

(benzo[a]acridin-12-yl)methyl 4-methoxybenzoate

Refernces