Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane

Base Information

• Chemical Name: Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane
• CAS No.: 36896-61-4
• Molecular Formula: C14H18O8Pb
• Molecular Weight: 521.492
• DSSTox Substance ID: DTXSID80586877
• Wikidata: Q82479097
• Mol file: 36896-61-4.mol

Synonyms:36896-61-4;Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane;DTXSID80586877;2,4-dimethoxyphenyllead triacetate

Chemical Property of Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane

Chemical Property:

• PSA: 138.85000
• LogP: -2.49570
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 9
• Exact Mass: 522.07682
• Heavy Atom Count: 23
• Complexity: 411

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)O[Pb](C1=C(C=C(C=C1)OC)OC)(OC(=O)C)OC(=O)C

Technology Process of Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane

There total 1 articles about Tris(acetyloxy)(2,4-dimethoxyphenyl)plumbane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

lead(IV) tetraacetate (546-67-8) + 1,3-Dimethoxybenzene (151-10-0) → 2,4-dimethoxyphenyllead triacetate (36896-61-4)

Guidance literature:

With chloroacetic acid; In chloroform; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1039/c2cc36452b

Reference yield: 98.0%

2,4-dimethoxyphenyllead triacetate (36896-61-4) + 4-Ethoxycarbonyl-2-phenyl-4,5-dihydrooxazol-5-one (153397-31-0) → 4-(2,4-Dimethoxyphenyl)-4-ethoxycarbonyl-2-phenyl-4,5-dihydrooxazol-5-one (189133-67-3)

Guidance literature:

With pyridine; In chloroform; at 40 ℃; for 1h;

Reference yield: 97.0%

2,4-dimethoxyphenyllead triacetate (36896-61-4) + 3-(allyloxycarbonyl)chroman-4-one (153488-86-9) → allyl 3-(2,4-dimethoxyphenyl)-4-oxochroman-3-carboxylate (153488-92-7)

Guidance literature:

With pyridine; In chloroform; at 40 ℃; for 12h;

upstream raw materials:

lead(IV) tetraacetate

1,3-Dimethoxybenzene

Downstream raw materials:

1-(2,4-dimethoxyphenyl)piperidine

1-(2,4-dimethoxyphenyl)-1,2,3,4-tetrahydroquinoline

2-(2,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

4-(2,4-Dimethoxy-phenyl)-3-hydroxy-chromen-2-one

Refernces

• 1、 Carroll, Michael P.,Mueller-Bunz, Helge,Guiry, Patrick J.. "Enantioselective construction of sterically hindered tertiary α-aryl ketones: A catalytic asymmetric synthesis of isoflavanones". supporting information. p. 11142 - 11144. Retrieved 2013/01/15.