Phloroglucinol monomethyl ether diacetate

Base Information

• Chemical Name: Phloroglucinol monomethyl ether diacetate
• CAS No.: 3727-22-8
• Molecular Formula: C11H12O5
• Molecular Weight: 224.213
• Mol file: 3727-22-8.mol

Synonyms:phloroglucinol monomethyl ether diacetate

Chemical Property of Phloroglucinol monomethyl ether diacetate

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 224.06847348
• Heavy Atom Count: 16
• Complexity: 239

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC(=CC(=C1)OC)OC(=O)C

Technology Process of Phloroglucinol monomethyl ether diacetate

There total 3 articles about Phloroglucinol monomethyl ether diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

5-methoxyresorcinol (2174-64-3) + acetyl chloride (75-36-5) → methyl diacetylphloroglucinol (3727-22-8)

Guidance literature:

With pyridine; In tetrahydrofuran;

DOI:10.1016/j.tet.2010.10.003

Reference yield:

5-methoxyresorcinol (2174-64-3) + acetic anhydride (108-24-7) → methyl diacetylphloroglucinol (3727-22-8)

Guidance literature:

With sodium acetate;

Reference yield:

→ methyl diacetylphloroglucinol (3727-22-8)

Guidance literature:

Phloroglucinolmonomethylether, Ac2O;

DOI:10.1039/jr9650002651

upstream raw materials:

5-methoxyresorcinol

acetic anhydride

acetyl chloride

Refernces