4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate

Base Information

• Chemical Name: 4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate
• CAS No.: 145071-46-1
• Molecular Formula: C14H15 Br N2 O3
• Molecular Weight: 339.1845
• Mol file: 145071-46-1.mol

Synonyms:BRN 5822163;1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-5-((methoxyimino)methyl)-, 4-bromophenyl ester, (E)-;4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate;145071-46-1;SCHEMBL9456962;LS-130888

Chemical Property of 4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 431.5°Cat760mmHg
• Flash Point: 214.7°C
• Density: 1.42g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 338.02660
• Heavy Atom Count: 20
• Complexity: 390

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CON=CC1=CCCN(C1)C(=O)OC2=CC=C(C=C2)Br
• Isomeric SMILES: CO/N=C/C1=CCCN(C1)C(=O)OC2=CC=C(C=C2)Br

Technology Process of 4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate

There total 1 articles about 4-Bromophenyl (E)-3,6-dihydro-5-((methoxyimino)methyl)-1(2H)-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-bromophenyl chloroformate (7693-44-9) + 1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-methyloxime hydrochloride (114485-47-1) → 5-(Methoxyimino-methyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid 4-bromo-phenyl ester (145071-46-1)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1016/0223-5234(92)90186-5

upstream raw materials:

4-bromophenyl chloroformate

1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-methyloxime hydrochloride

Refernces