4-(2-Bromoethoxy)benzophenone

Base Information

• Chemical Name: 4-(2-Bromoethoxy)benzophenone
• CAS No.: 38459-64-2
• Molecular Formula: C15H13BrO2
• Molecular Weight: 305.171
• DSSTox Substance ID: DTXSID20542513
• Nikkaji Number: J3.494.088F
• Wikidata: Q82419212
• Mol file: 38459-64-2.mol

Synonyms:4-(2-Bromoethoxy)benzophenone;38459-64-2;Methanone, [4-(2-bromoethoxy)phenyl]phenyl-;SCHEMBL6338785;DTXSID20542513;RGTVYJNIILDRKZ-UHFFFAOYSA-N;AKOS000197796;[4-(2-Bromoethoxy)phenyl](phenyl)methanone

Chemical Property of 4-(2-Bromoethoxy)benzophenone

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 304.00989
• Heavy Atom Count: 18
• Complexity: 253

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)OCCBr

Technology Process of 4-(2-Bromoethoxy)benzophenone

There total 2 articles about 4-(2-Bromoethoxy)benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

ethylene dibromide (106-93-4) + 4-Hydroxybenzophenone (1137-42-4) → (4-(2-bromoethoxy)phenyl)(phenyl)methanone (38459-64-2)

Guidance literature:

With sodium hydroxide; benzyl tri-n-butylammonium bromide; In water; for 18h; Heating;

Reference yield:

→ (4-(2-bromoethoxy)phenyl)(phenyl)methanone (38459-64-2)

Guidance literature:

p-Hydroxybenzophenon, 1,2-Dibromethan;

Reference yield: 83.0%

(4-(2-bromoethoxy)phenyl)(phenyl)methanone (38459-64-2) → 1,2-bis-[4-(2-bromoethoxy)phenyl]-1,2-diphenylethene

Guidance literature:

With titanium tetrachloride; zinc; In tetrahydrofuran; for 12h; Inert atmosphere; Reflux;

DOI:10.1039/c4cc02671c

upstream raw materials:

ethylene dibromide

4-Hydroxybenzophenone

Downstream raw materials:

1-(4-anilinophenyl)-2-(4-benzophenoxy)ethane

1-<4-(2-bromoethoxy)phenyl>-1,2-diphenylethanol

(Z)-1,1-dichloro-2,3-diphenyl-2-<4-(2-dimethylaminoethoxy)phenyl>cyclopropane

(Z/E)-1-<4-(2-bromoethoxy)phenyl>-1,2-diphenyl ethene

Refernces

• 1、 Murty,Katiki, Mohana Rao,Nanubolu, Jagadeesh Babu,Garimella, Srujana,Polepalli, Sowjanya,Jain, Nishant,Buddana, Sudheer Kumar,Prakasham. "Synthesis and biological evaluation of novel tamoxifen-1,2,4-triazole conjugates". . p. 687 - 703. Retrieved 2016.
• 2、 Xu, Li,Zhu, Zece,Zhou, Xiang,Qin, Jingui,Yang, Chuluo. "A highly sensitive nucleic acid stain based on amino-modified tetraphenylethene: The influence of configuration". supporting information. p. 6494 - 6497. Retrieved 2014/06/09.