1,10-Diiododecane

Base Information

• Chemical Name: 1,10-Diiododecane
• CAS No.: 16355-92-3
• Molecular Formula: C10H20I2
• Molecular Weight: 394.078
• Hs Code.: 2903399090
• European Community (EC) Number: 240-415-6
• DSSTox Substance ID: DTXSID5066035
• Nikkaji Number: J236.248A
• Wikidata: Q81992608
• Mol file: 16355-92-3.mol

Synonyms:1,10-Diiododecane;16355-92-3;Decane, 1,10-diiodo-;Decamethylene diiodide;C10H20I2;EINECS 240-415-6;MFCD00001086;EC 240-415-6;1,10-diiododecan;1,10-diiodo-Decane;1,10- di iododecane;1,10-Diiododecane, 95%;SCHEMBL482504;DTXSID5066035;AKOS015913438;C10-H20-I2;AS-57353;CS-0158373;D2439;FT-0606034;D83366;EN300-1709531;A810485;J-010057;F0001-0592

Chemical Property of 1,10-Diiododecane

Chemical Property:

• Appearance/Colour: yellow to brownish crystalline solid
• Vapor Pressure: 9.34E-05mmHg at 25°C
• Melting Point: 33-35 °C(lit.)
• Refractive Index: 1.555
• Boiling Point: 349.7 °C at 760 mmHg
• Flash Point: 146.7 °C
• PSA: 0.00000
• Density: 1.704 g/cm³
• LogP: 4.97720
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive
• Solubility.: Soluble in methanol.
• XLogP3: 6.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 9
• Exact Mass: 393.96545
• Heavy Atom Count: 12
• Complexity: 64.2

Purity/Quality:

99.9% ^*data from raw suppliers

1,10-Diiododecane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CCCCCI)CCCCI
• Uses: 1,10-Diiododecane is used as an alkylating agent in the synthesis of symmetrical and unsymmetrical bis-cryptophanes and as a crosslinking reagent for tetrabutylammonium polygalacturonic acid. it is also used to produce decane at temperature of 20°C. 1,10-Diiododecane has been used as:an alkylating agent in the synthesis of symmetrical and unsymmetrical bis-cryptophanescrosslinking reagent for tetrabutylammonium polygalacturonic acid

Technology Process of 1,10-Diiododecane

There total 13 articles about 1,10-Diiododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,10-dibromodecane (4101-68-2) → 1,10-diiododecane (16355-92-3)

Guidance literature:

With sodium iodide; In acetone; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.jmedchem.9b00595

Reference yield: 90.0%

1,10-Decanediol (112-47-0) → 1,10-diiododecane (16355-92-3)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In tetrahydrofuran; at -10 - 20 ℃; for 6h;

DOI:10.1016/S0040-4020(02)01063-3

Reference yield: 90.0%

1,10-dichlorodecane (2162-98-3) → 1,10-diiododecane (16355-92-3)

Guidance literature:

With sodium iodide; In acetone; for 24h; Heating;

DOI:10.1016/0022-328X(91)80253-G

upstream raw materials:

1,10-Decanediol

1,10-dichlorodecane

1,10-diphenoxy-decane

1,10-decanedioic acid

Downstream raw materials:

1,10-bis(phenylthio)decane

1,10-bis-heptafluorobutyryloxy-decane

1,12-dodecanedinitrile

decane

Refernces

• 1、 Qin, Donghui,Sullivan, Regina,Berkowitz, William F.,Bittman, Robert,Rotenberg, Susan A.. "Inhibition of protein kinase Cα by dequalinium analogues: Dependence on linker length and geometry". . p. 1413 - 1417. Retrieved 2000.
• 2、 Viras, Kyriakos,Viras, Fontini,Campbell, Carl,King, Terence A.,Booth, Colin. "Low-Frequency Raman Spectra of Even α,ο-Disubstituted n-Alkanes". . p. 3479 - 3483. Retrieved 1989.
• 3、 -. "BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME". Paragraph 00382; 00383. . Retrieved 2015/06/11.