N-Dodecylbenzamide

Base Information

• Chemical Name: N-Dodecylbenzamide
• CAS No.: 33140-65-7
• Molecular Formula: C19H31NO
• Molecular Weight: 289.461
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID80186795
• Nikkaji Number: J54.791C
• Wikidata: Q83058190
• Mol file: 33140-65-7.mol

Synonyms:N-Dodecylbenzamide;BENZAMIDE, N-DODECYL-;33140-65-7;BRN 2117826;3-09-00-01076 (Beilstein Handbook Reference);N-dodecyl-benzamide;SCHEMBL587375;DTXSID80186795;STK897828;AKOS003868433;LS-26791

Chemical Property of N-Dodecylbenzamide

Chemical Property:

• Vapor Pressure: 4.37E-08mmHg at 25°C
• Boiling Point: 444.2°Cat760mmHg
• Flash Point: 274.3°C
• PSA: 32.59000
• Density: 0.929g/cm³
• LogP: 5.91210
• XLogP3: 5.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 12
• Exact Mass: 289.240564612
• Heavy Atom Count: 21
• Complexity: 246

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNC(=O)C1=CC=CC=C1

Technology Process of N-Dodecylbenzamide

There total 30 articles about N-Dodecylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

n-Dodecylamine (124-22-1) + tert-butyl benzoyl(phenyl)carbamate (101137-69-3) → N-dodecylbenzamide (33140-65-7)

Guidance literature:

With triethylamine; In dichloromethane; at 23 ℃; for 15h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.7b00429

Reference yield: 98.0%

n-Dodecylamine (124-22-1) + N,N-phenyl-p-toluenesulfonylbenzamide (74542-54-4) → N-dodecylbenzamide (33140-65-7)

Guidance literature:

With triethylamine; In dichloromethane; at 23 ℃; for 15h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.7b00429

Reference yield: 97.0%

n-Dodecylamine (124-22-1) + N-benzoyl-N-benzyl-4-methylbenzenesulfonamide → N-dodecylbenzamide (33140-65-7)

Guidance literature:

In ethanol; at 45 ℃; chemoselective reaction; Sealed tube;

DOI:10.1055/s-0037-1610664

upstream raw materials:

n-Dodecylamine

benzoic acid ethyl ester

2-dodecyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

5-Phenyl-1H-tetrazole

Downstream raw materials:

N-Dodecyl-cyclohexylcarboxamid

n-Dodecylamine

benzoic acid

Refernces

• 1、 Ebrahimi, Edris,Khalafi-Nezhad, Ali,Khalili, Dariush,Rousta, Marzieh. "CuO-decorated magnetite-reduced graphene oxide: a robust and promising heterogeneous catalyst for the oxidative amidation of methylarenes in waterviabenzylic sp3C-H activation". . p. 20007 - 20020. Retrieved 2021/11/12.
• 2、 Ramkumar, Rajagopal,Chandrasekaran, Srinivasan. "Catalyst-Free, Metal-Free, and Chemoselective Transamidation of Activated Secondary Amides". . p. 921 - 932. Retrieved 2019/02/10.