DBD-COCL

Base Information

• Chemical Name: DBD-COCL
• CAS No.: 156153-43-4
• Molecular Formula: C11H13 Cl N4 O4 S
• Molecular Weight: 332.768
• Hs Code.: 2935009090
• Mol file: 156153-43-4.mol

Synonyms:Acetylchloride, [[7-[(dimethylamino)sulfonyl]-2,1,3-benzoxadiazol-4-yl]methylamino]-(9CI); 2,1,3-Benzoxadiazole, acetyl chloride deriv.

Chemical Property of DBD-COCL

Chemical Property:

• Vapor Pressure: 1.73E-09mmHg at 25°C
• Boiling Point: 483.1°C at 760 mmHg
• PKA: -2.53±0.50(Predicted)
• Flash Point: 245.9°C
• PSA: 104.99000
• Density: 1.503g/cm³
• LogP: 1.75550
• Storage Temp.: Freezer

Purity/Quality:

98%,99%, ^*data from raw suppliers

DBD-COCl[4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: DBD-COCl is used in fluorescent labelling HPLC analysis.

Technology Process of DBD-COCL

There total 1 articles about DBD-COCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H14N4O5S → 4-(N,N-dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole (156153-43-4)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/ol503044j

Reference yield: 55.0%

4-(N,N-dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole (156153-43-4) + 3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside} (145075-81-6) → C58H80N4O19S (1593111-61-5) + C58H80N4O19S

Guidance literature:

With dimethyltin dichloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1021/ol503044j

Reference yield: 17.0%

4-(N,N-dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole (156153-43-4) + 3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-{O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-(1->3)-2-O-acetyl-β-L-arabinopyranoside} (145075-81-6) → C58H80N4O19S (1593111-61-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at -78 - 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2014.02.009

Downstream raw materials:

C₅₈H₈₀N₄O₁₉S

Refernces