Cyclopropyl(4-pyridyl) ketone

Base Information

• Chemical Name: Cyclopropyl(4-pyridyl) ketone
• CAS No.: 39512-48-6
• Molecular Formula: C9H9NO
• Molecular Weight: 147.17400
• Mol file: 39512-48-6.mol

Synonyms:cyclopropyl 4-pyridinyl ketone;cyclopropyl(pyridin-4-yl)methanone;cyclopropyl-pyridin-4-yl-methanone;Cyclopropyl-4-pyridinyl-keton;cyclopropyl-4-pyridylmethanone;p-pyridinyl cyclopropyl ketone;

Chemical Property of Cyclopropyl(4-pyridyl) ketone

Chemical Property:

• Boiling Point: 86 - 90 °C (3 mmHg)
• PSA: 29.96000
• LogP: 1.67430

Purity/Quality:

95% ^*data from raw suppliers

Cyclopropyl(pyridin-4-yl)methanone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropyl(4-pyridyl) ketone

There total 5 articles about Cyclopropyl(4-pyridyl) ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-4-carbonitrile (100-48-1) + cyclopropylmagnesium bromide (23719-80-4) → cyclopropylpyridin-4-yl methanone (39512-48-6)

Guidance literature:

pyridine-4-carbonitrile; cyclopropylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃;

With hydrogenchloride; water; In tetrahydrofuran;

Reference yield:

cyclopropyl-4-pyridylcarbinol (317335-19-6) → cyclopropylpyridin-4-yl methanone (39512-48-6)

Guidance literature:

With manganese(IV) oxide; In chloroform; for 168h;

Reference yield:

pyridine-4-carbonitrile (100-48-1) + cyclopropyl bromide (4333-56-6,130561-87-4) + lithium (7439-93-2) → cyclopropylpyridin-4-yl methanone (39512-48-6)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

cyclopropyl-4-pyridylcarbinol

pyridine-4-carbonitrile

cyclopropyl bromide

lithium

Refernces

• 1、 -. "1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof". Page 75. . Retrieved 2010/02/06.
• 2、 -. "Imidazo[1,2-a]pyridines, and process for their preparation". . . Retrieved 2008/06/13.