2-Propynoic acid, 3-phenyl-, 3,5-dihydroxyphenyl ester

Base Information

• Chemical Name: 2-Propynoic acid, 3-phenyl-, 3,5-dihydroxyphenyl ester
• CAS No.: 396103-20-1
• Molecular Formula: C15H10O4
• Molecular Weight: 254.242
• Mol file: 396103-20-1.mol

Synonyms:

Chemical Property of 2-Propynoic acid, 3-phenyl-, 3,5-dihydroxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propynoic acid, 3-phenyl-, 3,5-dihydroxyphenyl ester

There total 2 articles about 2-Propynoic acid, 3-phenyl-, 3,5-dihydroxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylpropiolyl chloride (7299-58-3) + 3,5-dihydroxyphenol (108-73-6) → 3,5-dihydroxyphenyl-3-phenylpropynoate (396103-20-1)

Guidance literature:

With montmorillonite K-10; In nitrobenzene; at 70 ℃; for 12h;

DOI:10.1055/s-2001-18436

Reference yield:

phenylpropyolic acid (637-44-5) → 3,5-dihydroxyphenyl-3-phenylpropynoate (396103-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / CH₂Cl₂ / 2 h / Heating

2: 0.4 g / montmorillonite K-10 / nitrobenzene / 12 h / 70 °C

With thionyl chloride; montmorillonite K-10; In dichloromethane; nitrobenzene;

DOI:10.1055/s-2001-18436

Reference yield: 100.0%

3,5-dihydroxyphenyl-3-phenylpropynoate (396103-20-1) → 5,7-dihydroxy-2-phenyl-chromen-4-one (480-40-0)

Guidance literature:

With montmorillonite K-10; In nitrobenzene; at 120 ℃; for 12h;

DOI:10.1055/s-2001-18436

upstream raw materials:

phenylpropiolyl chloride

3,5-dihydroxyphenol

phenylpropyolic acid

Downstream raw materials:

5,7-dihydroxy-2-phenyl-chromen-4-one

Refernces