sulfuridazole

Base Information

• Chemical Name: sulfuridazole
• CAS No.: 1615-41-4
• Molecular Formula: C₅H₇N₃O₂S
• Molecular Weight: 173.195
• Hs Code.: 2933290090
• Mol file: 1615-41-4.mol

Synonyms:Imidazole,1-methyl-2-(methylthio)-5-nitro- (7CI,8CI);1-Methyl-2-methylthio-5-nitroimidazole; RSU 3043; Sulfuridazole

Chemical Property of sulfuridazole

Chemical Property:

• Vapor Pressure: 4.48E-05mmHg at 25°C
• Melting Point: 86-88 °C
• Boiling Point: 350.2°Cat760mmHg
• PKA: 0.93±0.25(Predicted)
• Flash Point: 165.6°C
• PSA: 88.94000
• Density: 1.46g/cm³
• LogP: 1.57340
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

1-Methyl-2-(methylthio)-5-nitro-1H-imidazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sulfuridazole

There total 2 articles about sulfuridazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-methylmercapto-3-methylimidazole (14486-52-3) → 1-methyl-2-(methylsulfanyl)-5-nitro-1H-imidazole (1615-41-4)

Guidance literature:

With nitric acid; for 1h;

DOI:10.1021/jm021030a

Reference yield:

→ 1-methyl-2-(methylsulfanyl)-5-nitro-1H-imidazole (1615-41-4)

Guidance literature:

1-Methyl-2-methylmercapto-imidazol, HNO3 conc.;

Reference yield: 90.0%

1-methyl-2-(methylsulfanyl)-5-nitro-1H-imidazole (1615-41-4) → 1-methyl-2-methylsulphonyl-5-nitro-imidazole (1615-53-8)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic acid; at 40 ℃; for 1h;

DOI:10.1021/jm021030a

upstream raw materials:

2-methylmercapto-3-methylimidazole

Downstream raw materials:

2-methanesulfinyl-1-methyl-5-nitro-1H-imidazole

1-methyl-2-methylsulphonyl-5-nitro-imidazole

Refernces

• 1、 Chauvière, Gérard,Bouteille, Bernard,Enanga, Bertin,De Albuquerque, Cristina,Croft, Simon L.,Dumas, Michel,Périé, Jacques. "Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead". . p. 427 - 440. Retrieved 2007/10/03.