2-Pyridinecarboxylic acid, 3-(benzoylamino)-, methyl ester

Base Information

• Chemical Name: 2-Pyridinecarboxylic acid, 3-(benzoylamino)-, methyl ester
• CAS No.: 400722-89-6
• Molecular Formula: C14H12N2O3
• Molecular Weight: 256.261
• Mol file: 400722-89-6.mol

Synonyms:

Chemical Property of 2-Pyridinecarboxylic acid, 3-(benzoylamino)-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pyridinecarboxylic acid, 3-(benzoylamino)-, methyl ester

There total 1 articles about 2-Pyridinecarboxylic acid, 3-(benzoylamino)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

methyl 3-aminopicolinate (36052-27-4) + benzoyl chloride (98-88-4) → methyl 3-benzoylaminopicolinate (400722-89-6)

Guidance literature:

With pyridine; dmap; In chloroform; for 22h; Heating;

DOI:10.1021/jo000993j

Reference yield: 33.0%

methyl 3-benzoylaminopicolinate (400722-89-6) → methyl 3-benzoylaminopicolinate N-oxide (400722-92-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In acetonitrile; for 2h;

DOI:10.1021/jo000993j

Reference yield:

methyl 3-benzoylaminopicolinate (400722-89-6) → 3-benzoylaminopicolinic acid N-oxide

Guidance literature:

Multi-step reaction with 2 steps

1: 33 percent / m-CPBA / acetonitrile / 2 h

2: 38 percent / NaOH / methanol; H₂O / 96 h / 20 °C

With sodium hydroxide; 3-chloro-benzenecarboperoxoic acid; In methanol; water; acetonitrile;

DOI:10.1021/jo000993j

upstream raw materials:

methyl 3-aminopicolinate

benzoyl chloride

Downstream raw materials:

methyl 3-benzoylaminopicolinate N-oxide

Refernces