1-AMINO-9-FLUORENONE

Base Information

• Chemical Name: 1-AMINO-9-FLUORENONE
• CAS No.: 6344-62-3
• Molecular Formula: C13H9NO
• Molecular Weight: 195.221
• Hs Code.: 2922399090
• European Community (EC) Number: 228-748-5
• NSC Number: 51311
• UNII: C5CL9U2GZY
• DSSTox Substance ID: DTXSID30212856
• Nikkaji Number: J81.196C
• Wikidata: Q72437020
• ChEMBL ID: CHEMBL1241133
• Mol file: 6344-62-3.mol

Synonyms:Fluoren-9-one,1-amino- (6CI,8CI);1-Amino-9H-fluoren-9-one;1-Aminofluorenone;NSC 51311;

Chemical Property of 1-AMINO-9-FLUORENONE

Chemical Property:

• Vapor Pressure: 8.3E-07mmHg at 25°C
• Melting Point: 118-120 °C(lit.)
• Refractive Index: 1.72
• Boiling Point: 406.2 °C at 760 mmHg
• Flash Point: 199.4 °C
• PSA: 43.09000
• Density: 1.327 g/cm³
• LogP: 3.06140
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 195.068413911
• Heavy Atom Count: 15
• Complexity: 276

Purity/Quality:

99% ^*data from raw suppliers

1-Amino-9-fluorenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(C2=O)C(=CC=C3)N

Technology Process of 1-AMINO-9-FLUORENONE

There total 23 articles about 1-AMINO-9-FLUORENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

9-oxo-fluorene-1-carboxylic acid amide (42135-37-5) → 1-amino-9H-fluoren-9-one (6344-62-3)

Guidance literature:

With sodium hydroxide; sodium bromite; In water; at 100 ℃; for 0.5h;

DOI:10.1246/cl.1984.713

Reference yield: 60.0%

1-nitro-9H-fluoren-9-one (56825-82-2) → 1-amino-9H-fluoren-9-one (6344-62-3)

Guidance literature:

With samarium; iodine; In methanol; for 6h; Heating;

DOI:10.1016/S0040-4039(98)01555-X

Reference yield: 55.0%

2-amino-4-phenylbenzene-1,3-dicarbonitrile (149379-76-0) → 1-amino-9H-fluoren-9-one (6344-62-3)

Guidance literature:

With PPA; at 100 ℃;

DOI:10.1016/S0040-4039(99)00370-6

upstream raw materials:

9-oxo-fluorene-1-carbonyl azide

1-nitro-9H-fluoren-9-one

1-Diacetylaminofluorenon

1-chloro-9H-fluoren-9-one

Downstream raw materials:

1-bromo-9H-fluoren-9-one

1-phenyl-9H-fluoren-9-one

1-phenyl-9H-fluorene

4-chloro-6-(10b-hydroxy-10bH-fluoreno[1,9-de][1,3]thiazin-2-yl)benzene-1,3-diol

Refernces

• 1、 Parker, Ariel N.,France, Stefan. "Completion of the Set: Synthesis of the (6,X′)-Flubromazepam Positional Isomers as Standards for Forensic Analysis". . p. 813 - 822. Retrieved 2021/12/27.
• 2、 Aidene, Mohand,Belkessam, Fatma,Soulé, Jean-Fran?ois,Doucet, Henri. "Reactivity of 2,1-Benzisoxazole in Palladium-Catalyzed Direct Arylation with Aryl Bromides". . p. 1583 - 1590. Retrieved 2016/05/02.