9-chloro-4,5-dimethylacridine

Base Information

• Chemical Name: 9-chloro-4,5-dimethylacridine
• CAS No.: 63345-58-4
• Molecular Formula: C₁₅H₁₂ClN
• Molecular Weight: 241.72
• Mol file: 63345-58-4.mol

Synonyms:

Chemical Property of 9-chloro-4,5-dimethylacridine

Chemical Property:

• Vapor Pressure: 1.76E-06mmHg at 25°C
• Boiling Point: 407.6°Cat760mmHg
• Flash Point: 232.7°C
• Density: 1.237g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-chloro-4,5-dimethylacridine

There total 4 articles about 9-chloro-4,5-dimethylacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4,5-dimethylacridone (59748-99-1) → 9-chloro-4,5-dimethylacridine (63345-58-4)

Guidance literature:

With trichlorophosphate; at 130 ℃; for 1.5h;

DOI:10.3390/60300230

Reference yield:

3-methyl-2-o-toluidino-benzoic acid (108716-22-9) → 9-chloro-4,5-dimethylacridine (63345-58-4)

Guidance literature:

With trichlorophosphate; at 120 ℃;

Reference yield:

2-methylphenyl bromide (95-46-5) → 9-chloro-4,5-dimethylacridine (63345-58-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; nitrobenzene; copper / 185 °C

2: phosphoryl chloride / 120 °C

With copper; potassium carbonate; nitrobenzene; trichlorophosphate;

upstream raw materials:

3-methyl-2-o-toluidino-benzoic acid

4,5-dimethylacridone

2-methylphenyl bromide

3-methylantranilic acid

Downstream raw materials:

4,5-Dimethyl-acridin

5-Amino-1,9-dimethylacridin

N-[4-(4,5-Dimethyl-acridin-9-ylamino)-3-methylamino-phenyl]-methanesulfonamide; hydrochloride

Refernces