4-CHLORO-BUTYRALDEHYDE

Base Information

• Chemical Name: 4-CHLORO-BUTYRALDEHYDE
• CAS No.: 6139-84-0
• Molecular Formula: C4H7ClO
• Molecular Weight: 106.552
• Mol file: 6139-84-0.mol

Synonyms:Butyraldehyde,4-chloro- (6CI,7CI,8CI);4-Chlorobutanal;4-Chlorobutyraldehyde;NSC 50473;g-Chlorobutyraldehyde;

Chemical Property of 4-CHLORO-BUTYRALDEHYDE

Chemical Property:

• Vapor Pressure: 2.68mmHg at 25°C
• Refractive Index: 1.41
• Boiling Point: 158 °C at 760 mmHg
• Flash Point: 51 °C
• PSA: 17.07000
• Density: 1.031g/cm³
• LogP: 1.20430

Purity/Quality:

99%, ^*data from raw suppliers

4-chlorobutanal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-BUTYRALDEHYDE

There total 21 articles about 4-CHLORO-BUTYRALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-Chloro-1-butanol (928-51-8) → 4-chlorobutyraldehyde (6139-84-0)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide; In dichloromethane; water; at 25 ℃; Electrolysis; Saturated solution;

DOI:10.1039/b815745f

Reference yield: 82.0%

4-Chlorobutanoyl chloride (4635-59-0) → 4-chlorobutyraldehyde (6139-84-0)

Guidance literature:

With pentacoordinated hydrogenosilane 1;

DOI:10.1016/S0040-4039(00)80274-9

Reference yield: 82.0%

Butane-1,4-diol (110-63-4) → 4-butanolide (96-48-0) + 4-chlorobutyraldehyde (6139-84-0)

Guidance literature:

With tetrachloromethane; bis(acetylacetonate)oxovanadium; at 100 ℃; for 1h;

DOI:10.1023/A:1021668011691

upstream raw materials:

5-chloro-pentane-1,2-diol

4-Chlorobutanoyl chloride

cyclobutyl p-toluenesulfonamide

4-chloro-butyric acid ethyl ester

Downstream raw materials:

4-chloro-1,1-diethoxybutane

4,7-Dimethyl-1,10-phenanthroline

4-methyl-8-nitroquinoline

4-chlorobutanal 2,4-dinitrophenylhydrazone

Refernces

• 1、 Iwase, Shoutaro,Kitamura, Masato,Suzuki, Yusuke,Tanaka, Shinji. "CpRu/Br?nsted Acid-Catalyzed Enantioselective Dehydrative Cyclization of Pyrroles N-Tethered with Allylic Alcohols". . . Retrieved 2020.
• 2、 Ghimire, Srijana,Fanwick, Phillip E.,McMillin, David R.. "DNA-binding studies of a tetraalkyl-substituted porphyrin and the mutually adaptive distortion principle". . p. 11108 - 11118. Retrieved 2014.
• 3、 Li, Shouming,Kosemura, Seiji,Yamamura, Shosuke. "Synthesis of the tricyclic ABC ring subunit of mazamine A". . p. 6661 - 6676. Retrieved 1998.
• 4、 -. "NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF". Paragraph 0562. . Retrieved 2020/06/08.