Amfenac

Base Information

• Chemical Name: Amfenac
• CAS No.: 51579-82-9
• Molecular Formula: C15H13NO3
• Molecular Weight: 255.273
• Hs Code.: 2922509090
• NSC Number: 309467
• UNII: 28O5C1J38A
• DSSTox Substance ID: DTXSID90199533
• Nikkaji Number: J11.225I
• Wikipedia: Amfenac
• Wikidata: Q4745976
• NCI Thesaurus Code: C73071
• ChEMBL ID: CHEMBL25146
• Mol file: 51579-82-9.mol

Synonyms:2-amino-3-benzoylbenzeneacetic acid, monosodium salt, monohydrate;AHR 5850;amfenac;amfenac calcium salt (2:1);amfenac monosodium salt;amfenac sodium

Chemical Property of Amfenac

Chemical Property:

• Melting Point: 121-123° (dec)
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 398.5°C (rough estimate)
• PSA: 80.39000
• Density: 1.1654 (rough estimate)
• LogP: 2.70810
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 255.08954328
• Heavy Atom Count: 19
• Complexity: 336

Purity/Quality:

99% ^*data from raw suppliers

Amfenac ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)O
• Uses: Anti-inflammatory.
• Therapeutic Function: Antiinflammatory

Technology Process of Amfenac

There total 4 articles about Amfenac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-benzoyl-1,3-dihydroindol-2-one (51135-38-7) → amfenac (51579-82-9)

Guidance literature:

With sodium hydroxide;

Reference yield:

oleic acid decyl ester (3687-46-5) → amfenac (51579-82-9)

Guidance literature:

Reference yield:

oleic acid oleylester (17363-94-9,27640-90-0,32142-11-3,125412-22-8,125412-23-9,3687-45-4) → amfenac (51579-82-9)

Guidance literature:

upstream raw materials:

7-benzoyl-1,3-dihydroindol-2-one

oleic acid decyl ester

oleic acid oleylester

Refernces

• 1、 -. "Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds". . . Retrieved 2008/06/13.