Acetamide, N,N-dimethyl-2-(phenylmethoxy)-

Base Information

• Chemical Name: Acetamide, N,N-dimethyl-2-(phenylmethoxy)-
• CAS No.: 41858-11-1
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Hs Code.: 2924299090
• Mol file: 41858-11-1.mol

Synonyms:2-benzyloxy-N,N-dimethylacetamide;benzooxazole-2-carboxylic acid dimethylamide;N,N-dimethyl-2-benzyloxyacetamide;2-Benzoxazolecarboxamide,N,N-dimethyl;Benzoxazole-2-carboxylic acid dimethyl-amide;N,N-dimethyl-2-benzoxazolecarboxamide;

Chemical Property of Acetamide, N,N-dimethyl-2-(phenylmethoxy)-

Chemical Property:

• PSA: 29.54000
• LogP: 1.29140

Purity/Quality:

95% ^*data from raw suppliers

2-Benzyloxy-N,N-dimethyl-acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetamide, N,N-dimethyl-2-(phenylmethoxy)-

There total 3 articles about Acetamide, N,N-dimethyl-2-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Benzyloxyacetyl chloride (19810-31-2) + N,N-dimethylammonium chloride (506-59-2) → 2-benzyloxy-N,N-dimethylacetamide (41858-11-1)

Guidance literature:

With triethylamine; In dichloromethane; at 23 ℃; for 1h;

DOI:10.1021/ol034815z

Reference yield:

benzyloxyacetic acid (30379-55-6) + dimethyl amine (124-40-3) → 2-benzyloxy-N,N-dimethylacetamide (41858-11-1)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; chloroform; at 20 ℃; for 16h;

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) + 2-chloro-N,N-dimethylacetamide (2675-89-0) → 2-benzyloxy-N,N-dimethylacetamide (41858-11-1)

Guidance literature:

With sodium hydride; In diethyl ether; Ambient temperature;

upstream raw materials:

benzyl alcohol

2-chloro-N,N-dimethylacetamide

Benzyloxyacetyl chloride

N,N-dimethylammonium chloride

Downstream raw materials:

2-hydroxy-N,N-dimethylacetamide

[1-(dimethylamino)ethylidene]bisphosphonic acid

benzyl-N,N-dimethylglycolamide

Refernces

• 1、 Haberman, Jannine M.,Gin, David Y.. "Dehydrative sialylation with C2-hemiketal sialyl donors". . p. 2539 - 2541. Retrieved 2007/10/03.