1-(Bromomethyl)-1-methylcyclopropane

Base Information

• Chemical Name: 1-(Bromomethyl)-1-methylcyclopropane
• CAS No.: 42082-19-9
• Molecular Formula: C5H9Br
• Molecular Weight: 149.02900
• DSSTox Substance ID: DTXSID90558909
• Wikidata: Q82441386
• Mol file: 42082-19-9.mol

Synonyms:42082-19-9;1-(bromomethyl)-1-methylcyclopropane;1-(Bromomethyl)-1-methyl-cyclopropane;Cyclopropane, 1-(bromomethyl)-1-methyl-;SCHEMBL6555583;DTXSID90558909;AKOS014313214;PB48049;PS-15664;D96531;EN300-129824;1-(BROMOMETHYL)-1-METHYL-CYCLOPROPANE(CONTAINS 60% THF SOLVENT)

Chemical Property of 1-(Bromomethyl)-1-methylcyclopropane

Chemical Property:

• PSA: 0.00000
• LogP: 2.18140
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 147.98876
• Heavy Atom Count: 6
• Complexity: 55

Purity/Quality:

99%, ^*data from raw suppliers

1-(bromomethyl)-1-methylcyclopropane 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC1)CBr

Technology Process of 1-(Bromomethyl)-1-methylcyclopropane

There total 3 articles about 1-(Bromomethyl)-1-methylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methylcyclopropanemethanol (2746-14-7) → 1-(Brommethyl)-1-methylcyclopropan (42082-19-9)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 20 ℃; for 48h; Cooling with ice;

Reference yield:

1-Methyl-cyclopropanoic acid (6914-76-7) → 1-(Brommethyl)-1-methylcyclopropan (42082-19-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 72 h / 20 °C

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 48 h / 20 °C / Cooling with ice

With sodium tetrahydroborate; carbon tetrabromide; boron trifluoride diethyl etherate; triphenylphosphine; In tetrahydrofuran; dichloromethane;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-methyl-3-bromo-1-propene (1458-98-6) → 1-(Brommethyl)-1-methylcyclopropan (42082-19-9)

Guidance literature:

Cu catalyst;

upstream raw materials:

diazomethane

2-methyl-3-bromo-1-propene

1-Methyl-cyclopropanoic acid

1-methylcyclopropanemethanol

Refernces