H-MET-OIPR HCL

Base Information

• Chemical Name: H-MET-OIPR HCL
• CAS No.: 85391-05-5
• Molecular Formula: C8H18ClNO2S
• Molecular Weight: 227.755
• Hs Code.: 2930909090
• Mol file: 85391-05-5.mol

Synonyms:L-Methionine,1-methylethyl ester, hydrochloride (9CI);L-Methionine isopropyl esterhydrochloride;Methionine isopropyl ester hydrochloride;

Chemical Property of H-MET-OIPR HCL

Chemical Property:

• Vapor Pressure: 0.000637mmHg at 25°C
• Boiling Point: 304.8 °C at 760 mmHg
• Flash Point: 138.1 °C
• PSA: 77.62000
• LogP: 2.52070
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

H-Met-OiPr.HCl 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-MET-OIPR HCL

There total 1 articles about H-MET-OIPR HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

L-methionine (63-68-3,26062-47-5,58576-49-1) + isopropyl alcohol (67-63-0,8013-70-5) → L-Methionine isopropyl ester hydrochloride (85391-05-5)

Guidance literature:

With thionyl chloride; at 0 ℃; Reflux;

DOI:10.1021/acsmedchemlett.6b00270

Reference yield: 89.0%

5-amino-2-[2-(4-fluorophenyl)ethyl benzoic acid] + L-Methionine isopropyl ester hydrochloride (85391-05-5) → isopropyl N-{5-amino-2-[2-(4-fluorophenyl)ethyl]benzoyl}-L-methioninate

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1-methyl-pyrrolidin-2-one; water; at 20 ℃; for 8h;

DOI:10.1021/jo701558y

Reference yield: 78.0%

2,3,4,5,6-pentafluorophenol (771-61-9) + L-Methionine isopropyl ester hydrochloride (85391-05-5) + O-phenyl phosphorodichloridate (770-12-7) → C20H21F5NO5PS

Guidance literature:

L-Methionine isopropyl ester hydrochloride; O-phenyl phosphorodichloridate; With triethylamine; In dichloromethane; at -78 - 0 ℃; for 4.5h;

2,3,4,5,6-pentafluorophenol; With triethylamine; In dichloromethane; at 0 ℃; for 4.33h;

DOI:10.1021/acsmedchemlett.6b00270

upstream raw materials:

L-methionine

isopropyl alcohol

Downstream raw materials:

C₄₆⁽¹⁴⁾C₆H₆₀N₃O₅FS₂

Refernces