diethyl 2-cyano-3-methyl-pentanedioate

Base Information

• Chemical Name: diethyl 2-cyano-3-methyl-pentanedioate
• CAS No.: 5832-70-2
• Molecular Formula: C11H17 N O4
• Molecular Weight: 227.26
• Mol file: 5832-70-2.mol

Synonyms:Glutaricacid, 2-cyano-3-methyl-, diethyl ester (6CI,7CI,8CI); Pentanedioic acid,2-cyano-3-methyl-, diethyl ester (9CI); NSC 166633; NSC 71509

Chemical Property of diethyl 2-cyano-3-methyl-pentanedioate

Chemical Property:

• Vapor Pressure: 0.000221mmHg at 25°C
• Boiling Point: 326°Cat760mmHg
• Flash Point: 141.9°C
• PSA: 76.39000
• Density: 1.075g/cm³
• LogP: 1.27858

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl 2-cyano-3-methyl-pentanedioate

There total 1 articles about diethyl 2-cyano-3-methyl-pentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-hydroxybutyrate (5405-41-4) + sodium cyanoacetic acid ethyl ester (18852-51-2) → 3-methyl glutaric acid (626-51-7) + diethyl 2-cyano-3-methylpentanedioate (5832-70-2)

Guidance literature:

With ethanol; durch Behandlung mit kalter konzentrierter Schwefelsaeure, Verduennung mit Wasser und Kochen;

Reference yield:

diethyl 2-cyano-3-methylpentanedioate (5832-70-2) → 3-methylglutaric anhydride (4166-53-4)

Guidance literature:

Multi-step reaction with 2 steps

1: bei der Verseifung

2: acetic acid anhydride / bei der Destillation

With acetic anhydride;

Reference yield:

diethyl 2-cyano-3-methylpentanedioate (5832-70-2) → 3-methyl glutaric acid (626-51-7)

Guidance literature:

With sulfuric acid;

upstream raw materials:

ethyl 3-hydroxybutyrate

sodium cyanoacetic acid ethyl ester

Downstream raw materials:

3-methyl glutaric acid

3-methylglutaric anhydride