2-methoxyethyl benzoate

Base Information

• Chemical Name: 2-methoxyethyl benzoate
• CAS No.: 5451-71-8
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol file: 5451-71-8.mol

Synonyms:

Chemical Property of 2-methoxyethyl benzoate

Chemical Property:

• Vapor Pressure: 0.0888mmHg at 25°C
• Boiling Point: 224.9°Cat760mmHg
• Flash Point: 86.4°C
• Density: 1.08g/cm³

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methoxyethyl benzoate

There total 21 articles about 2-methoxyethyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-chloroethyl methyl ether (627-42-9) + benzoyl chloride (98-88-4) → 2-methoxyethyl benzoate (5451-71-8)

Guidance literature:

With dmap; caesium carbonate; at 50 ℃; for 24h;

DOI:10.1021/acs.orglett.5b02479

Reference yield: 89.0%

ethylene glycol (107-21-1) + orthobenzoic acid trimethyl ester (707-07-3) → 2-methoxyethyl benzoate (5451-71-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃;

Reference yield: 85.0%

2-phenyl-1,3-dioxolane (936-51-6) → C9H10O3 (94-33-7) + 2-benzoyloxyethyl formate (33968-14-8) + 2-methoxyethyl benzoate (5451-71-8) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With oxygen; zinc(II) chloride; CoCl₂; In 1,2-dimethoxyethane; at 85 ℃; for 24h;

upstream raw materials:

2-methoxy-ethanol

benzoic acid

2-phenyl-2-methoxy-1,3-dioxolane

2-phenyl-1,3-dioxolane

Downstream raw materials:

1,5-diphenyl-1-pentanone

2-methoxy-ethanol

benzamide

benzoic acid

Refernces

• 1、 Smeyne, Dylan,Verboom, Katherine,Bryan, Maria,LoBue, James,Shaikh, Abid. "Electrochemical esterification via oxidative coupling of aldehydes and alcohols". supporting information. . Retrieved 2021/03/26.
• 2、 -. "Method for generating ester through reaction of benzoyl chloride and halogenated hydrocarbon". Paragraph 0033; 0034; 0035. . Retrieved 2017/08/31.