Carbanilide, 2-methoxy-

Base Information

• Chemical Name: Carbanilide, 2-methoxy-
• CAS No.: 13142-82-0
• Molecular Formula: C14H14N2O2
• Molecular Weight: 242.277
• Hs Code.: 2924299090
• NSC Number: 164409
• DSSTox Substance ID: DTXSID70304163
• Nikkaji Number: J103.058B
• Wikidata: Q82049895
• Mol file: 13142-82-0.mol

Synonyms:Carbanilide, 2-methoxy-;1-(2-methoxyphenyl)-3-phenylurea;13142-82-0;1-Phenyl-3-(2-methoxyphenyl)urea;Urea, N-(2-methoxyphenyl)-N'-phenyl-;N-(2-Methoxyphenyl)-N'-phenylurea;NSC 164409;2-Methoxycarbanilide;NSC164409;Cambridge id 7155893;Oprea1_295035;CBDivE_009961;DTXSID70304163;HMS1578N02;N-2-methoxyphenyl-N'-phenyl urea;STK387889;AKOS001305066;NSC-164409;SR-01000201787;SR-01000201787-1;Z44586340

Chemical Property of Carbanilide, 2-methoxy-

Chemical Property:

• Vapor Pressure: 0.00107mmHg at 25°C
• Boiling Point: 301.2°C at 760 mmHg
• Flash Point: 136°C
• PSA: 50.36000
• Density: 1.249g/cm³
• LogP: 3.48520
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 242.105527694
• Heavy Atom Count: 18
• Complexity: 265

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(2-METHOXYPHENYL)-3-PHENYLUREA Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1NC(=O)NC2=CC=CC=C2

Technology Process of Carbanilide, 2-methoxy-

There total 16 articles about Carbanilide, 2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-methoxy-phenylamine (90-04-0) + 3-phenyl-5H-1,4,2-dioxazol-5-one (19226-36-9) → N-(2-methoxyphenyl)-N'-phenyl-urea (13142-82-0)

Guidance literature:

With sodium acetate; In methanol; at 60 ℃; for 2h;

Reference yield: 91.0%

2-bromoanisole (578-57-4) + phenyl carbamate (64-10-8) → N-(2-methoxyphenyl)-N'-phenyl-urea (13142-82-0)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; (9,9-dimethyl-9H-xanthene-4,5-diyl)bis(bis(3,5-bis(trifluoromethyl)phenyl)phosphine); In 1,4-dioxane; at 100 ℃; for 1h;

DOI:10.1016/S0040-4039(03)01051-7

Reference yield: 89.0%

3-(2-methoxyphenyl)-1,4,2-dioxazole-5-one + aniline (62-53-3) → N-(2-methoxyphenyl)-N'-phenyl-urea (13142-82-0)

Guidance literature:

With sodium acetate; In methanol; at 60 ℃; for 2h;

upstream raw materials:

N-carboethoxyaniline

2-methoxy-phenylamine

phenyl isocyanate

ethyl N-(o-methoxyphenyl) carbamate

Downstream raw materials:

N-phenyl-N'-(2-hydroxylphenyl)urea

Refernces

• 1、 -. "Synthetic method and application of urea compound". Paragraph 0027-0028; 0030-0031. . Retrieved 2019/06/07.
• 2、 Sribalan, Rajendran,Sangili, Arumugam,Banuppriya, Govindharasu,Padmini, Vediappen. "An efficient synthesis of nitrile, tetrazole and urea from carbonyl compounds". . p. 3414 - 3421. Retrieved 2017/07/13.