Diethylsulfamide

Base Information

• Chemical Name: Diethylsulfamide
• CAS No.: 4841-33-2
• Molecular Formula: C4H12N2O2S
• Molecular Weight: 152.21500
• European Community (EC) Number: 696-523-2
• DSSTox Substance ID: DTXSID50563594
• Wikidata: Q82448064
• Mol file: 4841-33-2.mol

Synonyms:Diethylsulfamide;4841-33-2;(diethylsulfamoyl)amine;N,N-Diethyl-sulfamide;[ethyl(sulfamoyl)amino]ethane;MFCD11171676;n,n-diethylsulfamide;N,N-Diethylsulfuric diamide;SCHEMBL43035;DTXSID50563594;AKOS008092246;AT20312;FS-4988;SY066110;CS-0119667;EN300-62522;Z300108382

Chemical Property of Diethylsulfamide

Chemical Property:

• PSA: 71.78000
• LogP: 1.31280
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 152.06194880
• Heavy Atom Count: 9
• Complexity: 154

Purity/Quality:

95% ^*data from raw suppliers

Diethylsulfamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)S(=O)(=O)N

Technology Process of Diethylsulfamide

There total 5 articles about Diethylsulfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (N,N-diethylsulfamoyl)carbamate (182925-50-4) → N,N-diethylsulfamide (4841-33-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 1.5h;

Reference yield:

diethylamine (109-89-7) → N,N-diethylsulfamide (4841-33-2)

Guidance literature:

With SULFAMIDE; In 1,2-dimethoxyethane;

DOI:10.1021/jm00330a009

Reference yield:

N,N-diethylsulfamoyl chloride (20588-68-5) → N,N-diethylsulfamide (4841-33-2)

Guidance literature:

With ammonia;

upstream raw materials:

N,N-diethylsulfamoyl chloride

diethylamine

tert-butyl (N,N-diethylsulfamoyl)carbamate

Downstream raw materials:

1-Cyclohexyl-3-diaethylaminosulfonyl-harnstoff

3-Diethylaminosulfonyl-1-(4-dimethylamino-phenyl)-harnstoff

N-(2-chloro-4-fluoro-3-nitrobenzoyl)-N',N'-diethylsulfamide

C₂₃H₂₅FN₄O₃S

Refernces

• 1、 -. "SUBSTITUTED PYRAZOLO[1,5-A] PYRIDINE AS TROPOMYOSIN RECEPTOR KINASE (TRK) INHIBITORS". Paragraph 0599; 0600. . Retrieved 2015/01/06.
• 2、 -. "INHIBITORS OF HCV REPLICATION". Page/Page column 150-151. . Retrieved 2010/11/28.