Penicillin V sulfoxide

Base Information Edit

Chemical Name:Penicillin V sulfoxide
CAS No.:4888-90-8
Molecular Formula:C16H18N2O6S
Molecular Weight:366.395
Hs Code.:
European Community (EC) Number:225-507-6
DSSTox Substance ID:DTXSID20964130
Nikkaji Number:J724.646C
Mol file:4888-90-8.mol

Synonyms:penicillin V sulfoxide

Suppliers and Price of Penicillin V sulfoxide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Penicillin V sulfoxide Edit

Chemical Property:

Melting Point:167-168 °C (decomp)
Boiling Point:780.2°Cat760mmHg
PKA:2.61±0.60(Predicted)
Flash Point:425.6°C
PSA：132.22000
Density:1.54g/cm³
LogP:0.90710
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:366.08855747
Heavy Atom Count:25
Complexity:616

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(N2C(S1=O)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C
Isomeric SMILES:CC1([C@@H](N2[C@H](S1=O)[C@@H](C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C

Technology Process of Penicillin V sulfoxide

There total 17 articles about Penicillin V sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 65538-81-0
Penicillin-V-sulfoxid-1'-tert-butylaminocarbonyl-2',2',2'-trichlorethylester

: 4888-90-8
phenoxymethylpenicillin sulfoxide

Guidance literature:: With lithium cobalt(I)-phthalocyanine; phenol; In acetone; for 1h; Ambient temperature;

Reference yield:

: 4052-69-1
penicillin-V β-sulfoxide benzyl ester

: 4888-90-8
phenoxymethylpenicillin sulfoxide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; under 760 Torr;
DOI:10.1021/jo01051a061

Reference yield:

: 1256-06-0
(2S,5R,6R)-benzyl-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

: 4888-90-8
phenoxymethylpenicillin sulfoxide

Guidance literature:: Multi-step reaction with 2 steps

1: NaIO₄ / dioxane

2: H₂ / Pd-C / ethyl acetate / 760 Torr

With sodium periodate; hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethyl acetate;
DOI:10.1021/jo01051a061