Tetrafluorophthalic anhydride

Base Information

• Chemical Name: Tetrafluorophthalic anhydride
• CAS No.: 652-12-0
• Molecular Formula: C8F4O3
• Molecular Weight: 220.08
• Hs Code.: 29173990
• European Community (EC) Number: 211-485-5
• DSSTox Substance ID: DTXSID30215504
• Nikkaji Number: J205.930D
• Wikidata: Q72505232
• ChEMBL ID: CHEMBL2270551
• Mol file: 652-12-0.mol

Synonyms:Tetrafluorophthalic anhydride;652-12-0;3,4,5,6-tetrafluorophthalic anhydride;4,5,6,7-tetrafluoroisobenzofuran-1,3-dione;4,5,6,7-tetrafluoro-2-benzofuran-1,3-dione;1,3-isobenzofurandione, 4,5,6,7-tetrafluoro-;EINECS 211-485-5;52-12-0;Tetrafluorophthalicanhydride;MFCD00039697;SCHEMBL335922;C8F4O3;CHEMBL2270551;DTXSID30215504;Tetrafluoroisobenzofuran-1,3-dione;Tetrafluorophthalic anhydride, 97%;C8-F4-O3;3,4,5,6-Tetrafluorophtlic anhydride;AKOS005257989;DS-5861;AC-12288;FT-0632749;FT-0632750;T2381;EN300-1709294;tetrafluoro-1,3-dihydro-2-benzofuran-1,3-dione;W-104803;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16-chloro-11,17-dihydroxy-,(11b,16b)-(9ci);Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-16-chloro-11,17-dihydroxy-, (11b,16b)- (9CI)

Chemical Property of Tetrafluorophthalic anhydride

Chemical Property:

• Appearance/Colour: Light greyish to beige powder
• Vapor Pressure: 1.07mmHg at 25°C
• Melting Point: 94-96 °C(lit.)
• Refractive Index: 1.38
• Boiling Point: 332.6 °C at 760 mmHg
• Flash Point: 149.9 °C
• PSA: 43.37000
• Density: 1.843 g/cm³
• LogP: 1.55360
• Sensitive.: Moisture Sensitive
• Solubility.: Soluble in most organic solvents and acetic acid.
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 0
• Exact Mass: 219.97835651
• Heavy Atom Count: 15
• Complexity: 291

Purity/Quality:

99% ^*data from raw suppliers

Tetrafluorophthalic Anhydride >95.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C12=C(C(=C(C(=C1F)F)F)F)C(=O)OC2=O

Technology Process of Tetrafluorophthalic anhydride

There total 11 articles about Tetrafluorophthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3,4,5,6-tetrafluorophthalic acid (652-03-9) → 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione (652-12-0)

Guidance literature:

With thionyl chloride; at 90 ℃; for 14h;

DOI:10.1021/jo070404a

Reference yield: 95.2%

→ 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione (652-12-0) + 3,4,5,6-tetrafluorophthalic acid (652-03-9)

Guidance literature:

Reference yield: 93.4%

3,4,5,6-tetrafluorophthaloyldifluoride (5292-39-7) → 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione (652-12-0)

Guidance literature:

With sodium carbonate; In 5,5-dimethyl-1,3-cyclohexadiene;

upstream raw materials:

3,4,5,6-tetrafluorophthalic acid

3,4,5,6-tetrafluorophthaloyldifluoride

2,4 dichlorobenzoic acid

perfluorophthalide

Downstream raw materials:

2-benzoyl-3,4,5,6-tetrafluorobenzoic acid

3,4,6-trifluorophthalic acid

C₂₃H₁₅F₁₀N₃O₂S

N-(1,3,4,5,6,7,8-Heptafluoro-2-naphthyl)-3,4,5,6-tetrafluorophthalamic acid

Refernces

• 1、 Klimovich, Irina V.,Zhilenkov, Alexander V.,Кuznetsova, Lidiya I.,Frolova, Lubov A.,Yamilova, Olga R.,Troyanov, Sergey I.,Lyssenko, Konstantin A.,Troshin, Pavel A.. "Novel functionalized indigo derivatives for organic electronics". . . Retrieved 2020/11/24.
• 2、 Makhseed, Saad,Samuel, Jacob. "Hydrogen adsorption in microporous organic framework polymer". supporting information; experimental part. p. 4342 - 4344. Retrieved 2009/03/12.